3L9B
| Crystal Structure of Rat Otoferlin C2A | Descriptor: | MAGNESIUM ION, Otoferlin | Authors: | Helfmann, S, Neumann, P. | Deposit date: | 2010-01-04 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of the C2A domain of otoferlin reveals an unconventional top loop region. J.Mol.Biol., 406, 2011
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3NSJ
| The X-ray crystal structure of lymphocyte perforin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Law, R.H, Whisstock, J.C, Caradoc-Davies, T.T. | Deposit date: | 2010-07-01 | Release date: | 2010-11-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature, 468, 2010
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3M7F
| Crystal structure of the Nedd4 C2/Grb10 SH2 complex | Descriptor: | E3 ubiquitin-protein ligase NEDD4, Growth factor receptor-bound protein 10 | Authors: | Huang, Q, Szebenyi, M. | Deposit date: | 2010-03-16 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4. J.Biol.Chem., 285, 2010
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3N5A
| Synaptotagmin-7, C2B-domain, calcium bound | Descriptor: | CALCIUM ION, Synaptotagmin-7 | Authors: | Tomchick, D.R, Rizo, J, Craig, T.K. | Deposit date: | 2010-05-24 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.441 Å) | Cite: | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
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2KI6
| The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion | Descriptor: | Heparin-binding growth factor 1, Protein S100-A13, Synaptotagmin-1 | Authors: | Krishna, S.M, Rani, S.G, Yu, C. | Deposit date: | 2009-04-28 | Release date: | 2010-03-09 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion. J.Biol.Chem., 285, 2010
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3HN8
| Crystal structure of synaptotagmin | Descriptor: | CALCIUM ION, Synaptotagmin-3, ZINC ION | Authors: | Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. | Deposit date: | 2009-05-30 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat.Struct.Mol.Biol., 17, 2010
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3JZY
| Crystal structure of human Intersectin 2 C2 domain | Descriptor: | Intersectin 2, UNKNOWN ATOM OR ION | Authors: | Shen, Y, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-24 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure of human Intersectin 2 C2 domain To be Published
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3F05
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3F01
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3F04
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3F00
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2K4A
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2K45
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3GPE
| Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2 | Descriptor: | CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ... | Authors: | Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N. | Deposit date: | 2009-03-23 | Release date: | 2009-05-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2. Proc.Natl.Acad.Sci.USA, 106, 2009
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2K8M
| S100A13-C2A binary complex structure | Descriptor: | Protein S100-A13, Putative uncharacterized protein | Authors: | Mohan, S.K, Rani, S.G, Kumar, S.M, Yu, C. | Deposit date: | 2008-09-14 | Release date: | 2009-03-17 | Last modified: | 2012-04-18 | Method: | SOLUTION NMR | Cite: | S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway. Biochem.Biophys.Res.Commun., 380, 2009
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3FDW
| Crystal structure of a C2 domain from human synaptotagmin-like protein 4 | Descriptor: | Synaptotagmin-like protein 4 | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Miller, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-11-26 | Release date: | 2008-12-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a C2 domain from human synaptotagmin-like protein 4 To be Published
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3FBK
| Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A | Descriptor: | Regulator of G-protein signaling 3, SULFATE ION | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-11-19 | Release date: | 2008-12-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A To be Published
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2K3H
| Structural determinants for Ca2+ and PIP2 binding by the C2A domain of rabphilin-3A | Descriptor: | CALCIUM ION, Rabphilin-3A | Authors: | Coudevylle, N, Montaville, P, Leonov, A, Zweckstetter, M, Becker, S. | Deposit date: | 2008-05-08 | Release date: | 2008-10-21 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural Determinants for Ca2+ and Phosphatidylinositol 4,5-Bisphosphate Binding by the C2A Domain of Rabphilin-3A. J.Biol.Chem., 283, 2008
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2ZKM
| Crystal Structure of Phospholipase C Beta 2 | Descriptor: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION | Authors: | Hicks, S.N, Jezyk, M.R, Gershberg, S, Seifert, J.P, Harden, T.K, Sondek, J. | Deposit date: | 2008-03-26 | Release date: | 2008-08-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | General and versatile autoinhibition of PLC isozymes Mol.Cell, 31, 2008
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2Z0U
| Crystal structure of C2 domain of KIBRA protein | Descriptor: | WW domain-containing protein 1 | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2008-05-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of C2 domain of KIBRA protein To be Published
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3BXJ
| Crystal Structure of the C2-GAP Fragment of synGAP | Descriptor: | Ras GTPase-activating protein SynGAP | Authors: | Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K. | Deposit date: | 2008-01-14 | Release date: | 2008-03-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. Embo Rep., 9, 2008
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2R83
| Crystal structure analysis of human synaptotagmin 1 C2A-C2B | Descriptor: | CHLORIDE ION, Synaptotagmin-1 | Authors: | Sutton, R.B, Fuson, K.L, Montes, M, Robert, J.J. | Deposit date: | 2007-09-10 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association. Biochemistry, 46, 2007
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2ENP
| Solution structure of the first C2 domain from human B/K protein | Descriptor: | B/K protein | Authors: | Endo, H, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-28 | Release date: | 2007-10-02 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Solution structure of the first C2 domain from human B/K protein To be Published
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2EP6
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2JQZ
| Solution Structure of the C2 domain of human Smurf2 | Descriptor: | E3 ubiquitin-protein ligase SMURF2 | Authors: | Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D. | Deposit date: | 2007-06-15 | Release date: | 2007-09-11 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain Cell(Cambridge,Mass.), 130, 2007
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