2K4A

FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway

Summary for 2K4A

• Entry DOI: 10.2210/pdb2k4a/pdb
• Related: 2K43 2K45
• Descriptor: Synaptotagmin-1, Heparin-binding growth factor 1 (2 entities in total)
• Functional Keywords: beta barrel, fgf1-c2a binary complex, calcium, cell junction, cytoplasmic vesicle, glycoprotein, lipoprotein, membrane, metal-binding, palmitate, phosphoprotein, synapse, transmembrane, acetylation, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, protein transport
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21579; Secreted: P05230
• Total number of polymer chains: 2
• Total formula weight: 29901.93

Authors

Yu, C.,Mohan, S.K. (deposition date: 2008-06-02, release date: 2009-06-09, Last modification date: 2022-03-16)

• Primary citation: Mohan, S.K.,Yu, C.; FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release; To be Published,

Experimental method

SOLUTION NMR