3BXJ

Crystal Structure of the C2-GAP Fragment of synGAP

Summary for 3BXJ

Entry DOI	10.2210/pdb3bxj/pdb
Descriptor	Ras GTPase-activating protein SynGAP (1 entity in total)
Functional Keywords	gtpase activating protein, gtpase activation, membrane, phosphoprotein, sh3-binding, signaling protein
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Membrane; Peripheral membrane protein: Q9QUH6
Total number of polymer chains	2
Total formula weight	108890.97
Authors	Pena, V.,Hothorn, M.,Eberth, A.,Kaschau, N.,Parret, A.,Gremer, L.,Bonneau, F.,Ahmadian, M.R.,Scheffzek, K. (deposition date: 2008-01-14, release date: 2008-03-25, Last modification date: 2024-02-21)
Primary citation	Pena, V.,Hothorn, M.,Eberth, A.,Kaschau, N.,Parret, A.,Gremer, L.,Bonneau, F.,Ahmadian, M.R.,Scheffzek, K. The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. Embo Rep., 9:350-355, 2008 Cited by PubMed: 18323856 DOI: 10.1038/embor.2008.20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation