8FAM
 
 | | Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature | | 分子名称: | Synaptotagmin | | 著者 | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. | | 登録日 | 2022-11-28 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
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4RJ9
 | | Structure of a plant specific C2 domain protein, OsGAP1 from rice | | 分子名称: | C2 domain-containing protein-like, POTASSIUM ION | | 著者 | Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. | | 登録日 | 2014-10-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1).
J.Biol.Chem., 290, 2015
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6ANJ
 | | Synaptotagmin-7, C2A domain | | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4TS6
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6ANK
 | | Synaptotagmin-7, C2A- and C2B-domains | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6BTY
 | | Crystal structure of the PI3KC2alpha C2 domain in space group P41212 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | | 著者 | Chen, K.-E, Collins, B.M. | | 登録日 | 2017-12-08 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.678 Å) | | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
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6BTZ
 | | Crystal structure of the PI3KC2alpha C2 domain in space group C121 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... | | 著者 | Chen, K.-E, Collins, B.M. | | 登録日 | 2017-12-08 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
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6BU0
 | | Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Chen, K.-E, Collins, B.M. | | 登録日 | 2017-12-08 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.427 Å) | | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
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5A4X
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5A51
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5A50
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5A52
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3F05
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3FDW
 | | Crystal structure of a C2 domain from human synaptotagmin-like protein 4 | | 分子名称: | Synaptotagmin-like protein 4 | | 著者 | Bonanno, J.B, Rutter, M, Bain, K.T, Miller, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-11-26 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a C2 domain from human synaptotagmin-like protein 4
To be Published
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3F04
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3F00
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3F01
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3FBK
 | | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A | | 分子名称: | Regulator of G-protein signaling 3, SULFATE ION | | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-11-19 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
To be Published
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5CCJ
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3GPE
 | | Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2 | | 分子名称: | CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ... | | 著者 | Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N. | | 登録日 | 2009-03-23 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3HN8
 | | Crystal structure of synaptotagmin | | 分子名称: | CALCIUM ION, Synaptotagmin-3, ZINC ION | | 著者 | Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. | | 登録日 | 2009-05-30 | | 公開日 | 2010-02-23 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Nat.Struct.Mol.Biol., 17, 2010
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6KXT
 | | BON1-C2B | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Protein BONZAI 1, SULFATE ION | | 著者 | Wang, Q.C, Jiang, M.Q, Isupov, M.N, Sun, L.F, Wu, Y.K. | | 登録日 | 2019-09-12 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal Structure of an Arabidopsis Copine providing insights into this protein family
To be published
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6LCY
 | | Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | | 著者 | Zhang, Y, Zhang, X, Rao, F, Wang, C. | | 登録日 | 2019-11-20 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nat Metab, 3, 2021
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6NYT
 | | Munc13-1 C2B-domain, calcium bound | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | | 登録日 | 2019-02-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.369 Å) | | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Nat. Struct. Mol. Biol., 17, 2010
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6NYC
 | | Munc13-1 C2B-domain, calcium free | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Munc13-1 | | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | | 登録日 | 2019-02-11 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Nat. Struct. Mol. Biol., 17, 2010
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