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8B79
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BU of 8b79 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8KG9
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BU of 8kg9 by Molmil
Yeast replisome in state III
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG8
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BU of 8kg8 by Molmil
Yeast replisome in state II
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG6
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BU of 8kg6 by Molmil
Yeast replisome in state I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8J86
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BU of 8j86 by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
分子名称: CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*TP*)-3'), ...
著者Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C.
登録日2023-04-30
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structure of DNA replication machinery from human monkeypox virus in complex with a DNA duplex
To Be Published
8J8G
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BU of 8j8g by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and cidofovir diphosphate
分子名称: CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*T)-3'), ...
著者Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C.
登録日2023-05-01
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structural basis of human monkeypox viral DNA replication inhibition by brincidofovir and cidofovir
To Be Published
8J8F
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BU of 8j8f by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), ...
著者Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C.
登録日2023-05-01
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural basis of human monkeypox viral DNA replication inhibition by brincidofovir and cidofovir
To Be Published
8OJC
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BU of 8ojc by Molmil
HSV-1 DNA polymerase active site in alternative exonuclease state
分子名称: CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJD
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BU of 8ojd by Molmil
HSV-1 DNA polymerase beta-hairpin loop
分子名称: CALCIUM ION, DNA (47-MER), DNA (68-MER), ...
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJA
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BU of 8oja by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state
分子名称: CALCIUM ION, DNA (47-MER), DNA (68-MER), ...
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (1.87 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJ6
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BU of 8oj6 by Molmil
HSV-1 DNA polymerase-processivity factor complex in pre-translocation state
分子名称: DNA (22-MER), DNA (48-MER), DNA polymerase catalytic subunit, ...
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJ7
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BU of 8oj7 by Molmil
HSV-1 DNA polymerase-processivity factor complex in halted elongation state
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (53-MER), DNA (67-MER), ...
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJB
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BU of 8ojb by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site
分子名称: CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit
著者Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
登録日2023-03-24
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8QJ7
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BU of 8qj7 by Molmil
Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Yin, Z, Pellegrini, L.
登録日2023-09-12
公開日2024-02-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献CryoEM insights into RNA primer synthesis by the human primosome.
Febs J., 291, 2024
8Q3R
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BU of 8q3r by Molmil
Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus
分子名称: DNA polymerase, DNA polymerase processivity factor component OPG148, Uracil-DNA glycosylase
著者Burmeister, W.P, Ballandras-Colas, A, Boettcher, B, Grimm, C.
登録日2023-08-04
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus
To Be Published
8UCW
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BU of 8ucw by Molmil
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8UCV
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BU of 8ucv by Molmil
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8WPP
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BU of 8wpp by Molmil
Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA
分子名称: A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ...
著者Wang, X, Li, N, Gao, N.
登録日2023-10-10
公開日2023-11-29
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
8WPK
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BU of 8wpk by Molmil
Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ...
著者Wang, X, Li, N, Gao, N.
登録日2023-10-10
公開日2023-11-29
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
8WPE
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BU of 8wpe by Molmil
Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ...
著者Wang, X, Li, N, Gao, N.
登録日2023-10-10
公開日2023-11-29
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
8WPF
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BU of 8wpf by Molmil
Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ...
著者Wang, X, Li, N, Gao, N.
登録日2023-10-10
公開日2023-11-29
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
8V6I
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BU of 8v6i by Molmil
DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (14.06 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8V5N
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BU of 8v5n by Molmil
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-11-30
公開日2023-12-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (8.56 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8V6G
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BU of 8v6g by Molmil
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (11.16 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024

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件を2024-05-22に公開中

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