PDB: 367 件ウェブページステータス検索Chemie searchBIRD

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3FRJ	Crystal Structure of 11b-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Piperidyl Benzamide Inhibitor 分子名称: Corticosteroid 11-beta-Dehydrogenase, Isozyme 1, N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, ... 著者 Wang, Z, Sudom, A, Walker, N.P. 登録日 2009-01-08 公開日 2009-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3G1T	CRYSTAL STRUCTURE OF short chain dehydrogenase from Salmonella enterica subsp. enterica serovar Typhi str. CT18 分子名称: MAGNESIUM ION, short chain dehydrogenase 著者 Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-01-30 公開日 2009-02-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 CRYSTAL STRUCTURE OF short chain dehydrogenase from Salmonella enterica subsp. enterica serovar Typhi str. CT18 To be Published
3G49	N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275 分子名称: 11-beta-hydroxysteroid dehydrogenase 1, 2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Pauly, T.A. 登録日 2009-02-03 公開日 2009-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275. Bioorg.Med.Chem.Lett., 19, 2009
3GZ4	Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH 分子名称: Hypothetical oxidoreductase yciK, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-06 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH To be Published
3HB4	17beta-hydroxysteroid dehydrogenase type1 complexed with E2B 分子名称: 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, Estradiol 17-beta-dehydrogenase 1 著者 Mazumdar, M, Fournier, D, Zhu, D.-W, Cadot, C, Poirier, D, Lin, S.-X. 登録日 2009-05-04 公開日 2009-12-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. Biochem.J., 424, 2009
3GMD	Structure-based design of 7-Azaindole-pyrrolidines as inhibitors of 11beta-Hydroxysteroid-Dehydrogenase type I 分子名称: 2-methyl-3-{(3S)-1-[(1-pyridin-2-ylcyclopropyl)carbonyl]pyrrolidin-3-yl}-1H-pyrrolo[2,3-b]pyridine, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Valeur, E, Lepifre, F, Roche, D, Christmann-Franck, S, Hillertz, P, Musil, D. 登録日 2009-03-13 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11 beta-hydroxysteroid dehydrogenase type I. Bioorg.Med.Chem.Lett., 22, 2012
7ONU	Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr 分子名称: 3-hydroxyacyl-CoA dehydrogenase type-2, MAGNESIUM ION, Mitochondrial Precursor tRNA-Tyr, ... 著者 Bhatta, A, Dienemann, C, Cramer, P, Hillen, H.S. 登録日 2021-05-26 公開日 2021-08-11 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of RNA processing by human mitochondrial RNase P. Nat.Struct.Mol.Biol., 28, 2021
2XOX	Crystal structure of pteridine reductase (PTR1) from Leishmania donovani 分子名称: PTERIDINE REDUCTASE, SULFATE ION 著者 Barrack, K.L, Tulloch, L.B, Burke, L.A, Fyfe, P.K, Hunter, W.N. 登録日 2010-08-24 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Recombinant Leishmania Donovani Pteridine Reductase Reveals a Disordered Active Site. Acta Crystallogr.,Sect.F, 67, 2011
5L53	Menthone neomenthol reductase from Mentha piperita in complex with NADP 分子名称: (-)-menthone:(+)-neomenthol reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-05-27 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
2CDH	ARCHITECTURE OF THE THERMOMYCES LANUGINOSUS FUNGAL FATTY ACID SYNTHASE AT 5 ANGSTROM RESOLUTION. 分子名称: DEHYDRATASE, ENOYL REDUCTASE, KETOACYL REDUCTASE, ... 著者 Jenni, S, Leibundgut, M, Maier, T, Ban, N. 登録日 2006-01-24 公開日 2006-03-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Architecture of a Fungal Fatty Acid Synthase at 5 A Resolution. Science, 311, 2006
5L51	Menthone neomenthol reductase from Mentha piperita 分子名称: (-)-menthone:(+)-neomenthol reductase 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-05-27 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
2DKN	Crystal structure of the 3-alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 complexed with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-alpha-hydroxysteroid dehydrogenase 著者 Nakamura, S. 登録日 2006-04-12 公開日 2006-08-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Apo- and Holo-structures of 3{alpha}-Hydroxysteroid Dehydrogenase from Pseudomonas sp. B-0831: LOOP-HELIX TRANSITION INDUCED BY COENZYME BINDING J.Biol.Chem., 281, 2006
1FJH	THE CRYSTAL STRUCTURE OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY 分子名称: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE 著者 Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. 登録日 2000-08-08 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275, 2000
1FK8	THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY 分子名称: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. 登録日 2000-08-09 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275, 2000
3O26	The structure of salutaridine reductase from Papaver somniferum. 分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Salutaridine reductase 著者 Higashi, Y, Kutchen, T.M, Smith, T.J. 登録日 2010-07-22 公開日 2010-12-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 The atomic structure of salutaridine reductase from the opium poppy Papaver somniferum. J.Biol.Chem., 66, 2010
3OML	Structure of full-length peroxisomal multifunctional enzyme type 2 from Drosophila melanogaster 分子名称: Peroxisomal Multifunctional Enzyme Type 2, CG3415 著者 Haataja, T.J.K, Koski, M.K, Glumoff, T, Hiltunen, J.K. 登録日 2010-08-27 公開日 2011-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Peroxisomal multifunctional enzyme type 2 from the fruitfly: dehydrogenase and hydratase act as separate entities, as revealed by structure and kinetics. Biochem.J., 435, 2011
3WYE	Crystal Structure of chimeric engineered (2S,3S)-butanediol dehydrogenase complexed with NAD+ 分子名称: Diacetyl reductase [(S)-acetoin forming],L-2,3-butanediol dehydrogenase,Diacetyl reductase [(S)-acetoin forming],L-2,3-butanediol dehydrogenase,Diacetyl reductase [(S)-acetoin forming],L-2,3-butanediol dehydrogenase,Diacetyl reductase [(S)-acetoin forming], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Shimegi, T, Oyama, T, Kusunoki, M, Ui, S. 登録日 2014-08-26 公開日 2015-08-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal Structure of chimeric engineered (2S,3S)-butanediol dehydrogenase complexed with NAD+ To be Published

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