1FK8
THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY
Summary for 1FK8
Entry DOI | 10.2210/pdb1fk8/pdb |
Related | 1FJH |
Descriptor | 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
Functional Keywords | short chain dehydrogenase, sdr, carbonyl reductase, steroid, hydroxysteroid, xenobiotic, metyrapone, oligomerisation, comamonas testosteroni, nad, nicotinamide adenine dinucleotide, substrate binding loop, oxidoreductase |
Biological source | Comamonas testosteroni |
Total number of polymer chains | 2 |
Total formula weight | 54167.71 |
Authors | Grimm, C.,Ficner, R.,Maser, E.,Klebe, G.,Reuter, K. (deposition date: 2000-08-09, release date: 2001-01-17, Last modification date: 2024-02-07) |
Primary citation | Grimm, C.,Maser, E.,Mobus, E.,Klebe, G.,Reuter, K.,Ficner, R. The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275:41333-41339, 2000 Cited by PubMed: 11007791DOI: 10.1074/jbc.M007559200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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