PDB: 110 resultsInfo pagesStatus searchChemie searchBIRD

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7XV8	Crystal structure of the Human TR4 DNA-Binding Domain Homodimer Bound to DR1 Response Element Descriptor: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), Nuclear receptor subfamily 2 group C member 2, ... Authors: Liu, Y, Chen, Z. Deposit date: 2022-05-21 Release date: 2022-12-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.199 Å) Cite: Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
7XV9	Crystal structure of the Human TR4 DNA-Binding Domain Descriptor: Nuclear receptor subfamily 2 group C member 2, ZINC ION Authors: Liu, Y, Chen, Z. Deposit date: 2022-05-21 Release date: 2022-12-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.599 Å) Cite: Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
7XVN	Structural basis for DNA recognition feature of retinoid-related orphan receptors Descriptor: DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Nuclear receptor ROR-gamma, ... Authors: Chen, Y, Jiang, L. Deposit date: 2022-05-24 Release date: 2023-11-29 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (2.302 Å) Cite: Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
8CEF	Asymmetric Dimerization in a Transcription Factor Superfamily is Promoted by Allosteric Interactions with DNA Descriptor: DNA (26-MER), Nuclear receptor DNA binding domain, ZINC ION Authors: Patel, A.K.M, Shaik, T.B, McEwen, A.G, Moras, D, Klaholz, B.P, Billas, I.M.L. Deposit date: 2023-02-01 Release date: 2023-08-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.486 Å) Cite: Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA. Nucleic Acids Res., 51, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... Authors: Noddings, C.M, Agard, D.A. Deposit date: 2022-12-10 Release date: 2023-11-01 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... Authors: Noddings, C.M, Agard, D.A. Deposit date: 2022-12-10 Release date: 2023-11-01 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8HBM	Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA Descriptor: Bile acid receptor, DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*AP*TP*GP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*TP*TP*GP*AP*CP*CP*TP*CP*G)-3'), ... Authors: Jiang, L, Chen, Y. Deposit date: 2022-10-29 Release date: 2023-06-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA. Comput Struct Biotechnol J, 21, 2023
8IFO	Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter Descriptor: DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ... Authors: Xu, T, Zhen, X, Liu, J. Deposit date: 2023-02-19 Release date: 2023-03-29 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element. Biochem.Biophys.Res.Commun., 656, 2023
8J54	Crystal structure of RXR/DR2 complex Descriptor: DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... Authors: Chen, Y, Jiang, L. Deposit date: 2023-04-21 Release date: 2024-01-17 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
8PKI	Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 Descriptor: DNA, Histone H2A, Histone H2B type 1-C/E/G, ... Authors: Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. Deposit date: 2023-06-26 Release date: 2024-02-28 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 2024

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