8BFJ
 
 | | CNOT11-GGNBP2 complex | | Descriptor: | 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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8BFI
 | | human CNOT1-CNOT10-CNOT11 module | | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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8BFH
 | | CNOT11 | | Descriptor: | CCR4-NOT transcription complex subunit 11 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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8C0T
 | | NRS 1.2: Fluorescent Sensors for Imaging Interstitial Calcium | | Descriptor: | CALCIUM ION, SULFATE ION, mNeonGreen,Optimized Ratiometric Calcium Sensor | | Authors: | Basquin, J, Griesbeck, O, Valiente-Gabioud, A. | | Deposit date: | 2022-12-19 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Fluorescent sensors for imaging of interstitial calcium.
Nat Commun, 14, 2023
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6YVH
 | | CWC22-CWC27-EIF4A3 Complex | | Descriptor: | Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog | | Authors: | Basquin, J, Busetto, V, LeHir, H, Conti, E. | | Deposit date: | 2020-04-28 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
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7OGG
 | | Nse5/6 complex | | Descriptor: | DNA repair protein KRE29,DNA repair protein KRE29,DNA repair protein KRE29, Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5 | | Authors: | Basquin, J, Taschner, M, Gruber, S. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.
Embo J., 40, 2021
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | Authors: | Basquin, J, Oezguer, S, Conti, E. | | Deposit date: | 2015-09-08 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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7OCZ
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7OCX
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4B8C
 | | nuclease module of the yeast Ccr4-Not complex | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR, POLY(A) RIBONUCLEASE POP2 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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2YHT
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4B8B
 | | N-Terminal domain of the yeast Not1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GOLD ION | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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2Y90
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4B8A
 | | Structure of yeast NOT1 MIF4G domain co-crystallized with CAF1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, POLY(A) RIBONUCLEASE POP2 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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4B89
 | | MIF4G domain of the yeast Not1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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2WP8
 | | yeast rrp44 nuclease | | Descriptor: | CHLORIDE ION, EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, ... | | Authors: | Basquin, J, Bonneau, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2009-08-03 | | Release date: | 2009-11-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation.
Cell(Cambridge,Mass.), 139, 2009
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4CT7
 | | CNOT9-CNOT1 complex with bound tryptophan | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, ... | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2014-03-12 | | Release date: | 2014-05-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.897 Å) | | Cite: | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
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4CV5
 | | yeast NOT1 CN9BD-CAF40 complex | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, HEXATANTALUM DODECABROMIDE, PROTEIN CAF40 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2014-03-23 | | Release date: | 2014-05-07 | | Last modified: | 2014-06-18 | | Method: | X-RAY DIFFRACTION (3.807 Å) | | Cite: | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
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4CT6
 | | CNOT9-CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2014-03-12 | | Release date: | 2014-05-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
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6XWY
 | | Highly pH-resistant long stokes-shift, red fluorescent protein mCRISPRed | | Descriptor: | 1,2-ETHANEDIOL, MALONIC ACID, Red fluorescent protein eqFP611 | | Authors: | Erdogan, M, Fabritius, A, Basquin, J, Griesbeck, O. | | Deposit date: | 2020-01-24 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Targeted In Situ Protein Diversification and Intra-organelle Validation in Mammalian Cells.
Cell Chem Biol, 27, 2020
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5NKM
 | | SMG8-SMG9 complex | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Li, L, Basquin, J, Conti, E. | | Deposit date: | 2017-03-31 | | Release date: | 2017-04-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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8PKI
 | | Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 | | Descriptor: | DNA, Histone H2A, Histone H2B type 1-C/E/G, ... | | Authors: | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | | Deposit date: | 2023-06-26 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.58 Å) | | Cite: | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.
Nat.Struct.Mol.Biol., 2024
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8PKJ
 | | Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5 | | Descriptor: | DNA, Histone H2A, Histone H2B, ... | | Authors: | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | | Deposit date: | 2023-06-26 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.
Nat.Struct.Mol.Biol., 2024
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7AQO
 | | yeast THO-Sub2 complex dimer | | Descriptor: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | | Deposit date: | 2020-10-22 | | Release date: | 2020-12-02 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
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7APX
 | | yeast THO-Sub2 complex | | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... | | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | | Deposit date: | 2020-10-20 | | Release date: | 2020-12-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
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