8FFV
Cryo-EM structure of the GR-Hsp90-FKBP52 complex
Summary for 8FFV
| Entry DOI | 10.2210/pdb8ffv/pdb |
| EMDB information | 29068 29069 |
| Descriptor | Heat shock protein HSP 90-alpha, Glucocorticoid receptor, Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed, ... (6 entities in total) |
| Functional Keywords | chaperone, steroid hormone receptor, ligand binding, atp binding, protein folding |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 263831.99 |
| Authors | Noddings, C.M.,Agard, D.A. (deposition date: 2022-12-10, release date: 2023-11-01, Last modification date: 2023-12-20) |
| Primary citation | Noddings, C.M.,Johnson, J.L.,Agard, D.A. Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30:1867-1877, 2023 Cited by PubMed: 37945740DOI: 10.1038/s41594-023-01128-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.01 Å) |
Structure validation
Download full validation report
