5KBK
 
 | | Candida Albicans Superoxide Dismutase 5 (SOD5), E110A Mutant | | 分子名称: | COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION | | 著者 | Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J. | | 登録日 | 2016-06-03 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.411 Å) | | 主引用文献 | The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases.
J.Biol.Chem., 291, 2016
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4U4I
 | | Megavirus chilensis superoxide dismutase | | 分子名称: | Cu/Zn superoxide dismutase | | 著者 | Lartigue, A, Claverie, J.-M, Burlat, B, Coutard, B, Abergel, C. | | 登録日 | 2014-07-23 | | 公開日 | 2014-11-05 | | 最終更新日 | 2014-12-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The megavirus chilensis cu,zn-superoxide dismutase: the first viral structure of a typical cellular copper chaperone-independent hyperstable dimeric enzyme.
J.Virol., 89, 2015
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2R27
 | | Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S | | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn] | | 著者 | Roberts, B.R, Getzoff, E.D, Karplus, P.A, Beckman, J.S, Tainer, J.A. | | 登録日 | 2007-08-24 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS.
J.Mol.Biol., 373, 2007
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3CE1
 | | Crystal Structure of the Cu/Zn Superoxide Dismutase from Cryptococcus liquefaciens Strain N6 | | 分子名称: | ACETATE ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Teh, A.H, Kanamasa, S, Kajiwara, S, Kumasaka, T. | | 登録日 | 2008-02-27 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure of Cu/Zn superoxide dismutase from the heavy-metal-tolerant yeast Cryptococcus liquefaciens strain N6.
Biochem.Biophys.Res.Commun., 374, 2008
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8JD8
 | | Crystal structure of Citrus limon Cu-Zn superoxide dismutase | | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T. | | 登録日 | 2023-05-12 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon.
Acta Crystallogr.,Sect.F, 79, 2023
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8Q6M
 | | Human SOD1 low dose data collecton | | 分子名称: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | 登録日 | 2023-08-14 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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4XCR
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | | 分子名称: | Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | | 登録日 | 2014-12-18 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.602 Å) | | 主引用文献 | Thermodynamics of protein destabilization in live cells.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
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4FF9
 | | Crystal Structure of cysteinylated WT SOD1. | | 分子名称: | COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ... | | 著者 | Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N. | | 登録日 | 2012-05-31 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5003 Å) | | 主引用文献 | Structural consequences of cysteinylation of cu/zn-superoxide dismutase.
Biochemistry, 52, 2013
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7NXX
 | | Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). | | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | | 著者 | Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. | | 登録日 | 2021-03-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1
To Be Published
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8CCX
 | | Human SOD1 in complex with S-XL6 cross-linker | | 分子名称: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | 登録日 | 2023-01-27 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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5CU9
 | | CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO | | 分子名称: | Cell surface Cu-only superoxide dismutase 5, SULFATE ION | | 著者 | Waninger-Saroni, J.J, Taylor, A.B, Hart, P.J, Galaleldeen, A. | | 登録日 | 2015-07-24 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO
To Be Published
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3KM1
 | | ZINC-Reconstituted TOMATO CHLOROPLAST SUPEROXIDE DISMUTASE | | 分子名称: | GLYCEROL, Superoxide dismutase [Cu-Zn], chloroplastic, ... | | 著者 | Galaleldeen, A, Taylor, A.B, Thomas, S.T, Hart, P.J. | | 登録日 | 2009-11-09 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biophysical properties of tomato chloroplast sod
To be Published
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3KM2
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6A9O
 | | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis | | 分子名称: | 2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid, DIMETHYL SULFOXIDE, Dihydrogen tetrasulfide, ... | | 著者 | Manjula, R, Padmanabhan, B. | | 登録日 | 2018-07-14 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis.
J.Biomol.Struct.Dyn., 37, 2019
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5O40
 | | SOD1 bound to Ebselen | | 分子名称: | N-phenyl-2-selanylbenzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | | 登録日 | 2017-05-25 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.
Nat Commun, 9, 2018
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6VBS
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5O3Y
 | | SOD1 bound to Ebsulfur | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | | 登録日 | 2017-05-25 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.
Nat Commun, 9, 2018
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6VBT
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4OH2
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4OJA
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7XX3
 | | Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) | | 分子名称: | (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Padmanabhan, B, Unni, S. | | 登録日 | 2022-05-28 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
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8GSQ
 | | Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. | | 分子名称: | (9~{R})-3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-9-oxidanyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | | 著者 | Aouti, S, Padmanabhan, B. | | 登録日 | 2022-09-06 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based discovery of an antipsychotic drug, paliperidone, as a modulator of human superoxide dismutase 1: a potential therapeutic target in amyotrophic lateral sclerosis.
Acta Crystallogr D Struct Biol, 79, 2023
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7YPP
 | | Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | | 分子名称: | CALCIUM ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | | 登録日 | 2022-08-04 | | 公開日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1.
Acta Crystallogr.,Sect.F, 79, 2023
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7YPR
 | | Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | | 分子名称: | COPPER (II) ION, POTASSIUM ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | | 登録日 | 2022-08-04 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1.
Acta Crystallogr.,Sect.F, 79, 2023
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5YTU
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