3WUW
| KIR3DL1 in complex with HLA-B*57:01.I80T | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Vivian, J.P, Rossjohn, J. | Deposit date: | 2014-05-06 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity J.Immunol., 192, 2014
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2MOV
| Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs. | Descriptor: | Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine | Authors: | Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R. | Deposit date: | 2014-05-05 | Release date: | 2014-06-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs. Biochemistry, 53, 2014
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3J70
| Model of gp120, including variable regions, in complex with CD4 and 17b | Descriptor: | Envelope glycoprotein gp120, T-cell surface glycoprotein CD4, envelope glycoprotein gp41, ... | Authors: | Rasheed, M, Bettadapura, R, Bajaj, C. | Deposit date: | 2014-04-22 | Release date: | 2015-08-26 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State. Structure, 23, 2015
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4Q6I
| Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4 | Descriptor: | Heavy chain of murine 2D5 Fab, Light chain of murine 2D5 Fab, T-cell surface glycoprotein CD4 | Authors: | Boyington, J.C, Nabel, G.J, Mascola, J.R. | Deposit date: | 2014-04-22 | Release date: | 2014-07-23 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Sci Transl Med, 6, 2014
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4PBV
| Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform, ... | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | Deposit date: | 2014-04-14 | Release date: | 2014-11-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis. Nat Commun, 5, 2014
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4PBW
| Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | Deposit date: | 2014-04-14 | Release date: | 2014-11-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis. Nat Commun, 5, 2014
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4P9H
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4P2Y
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4OI7
| RAGE recognizes nucleic acids and promotes inflammatory responses to DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ... | Authors: | Jin, T, Jiang, J, Xiao, T. | Deposit date: | 2014-01-19 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.104 Å) | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
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4OI8
| RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. | Descriptor: | 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', Advanced glycosylation end product-specific receptor | Authors: | Jin, T, Jiang, J, Xiao, T. | Deposit date: | 2014-01-19 | Release date: | 2014-04-30 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
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2MJW
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4OFV
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4OF5
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4N8V
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4LP4
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4LP5
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4LLA
| Crystal structure of D3D4 domain of the LILRB2 molecule | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 2 | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | Deposit date: | 2013-07-09 | Release date: | 2013-09-11 | Last modified: | 2013-11-06 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding Protein Cell, 4, 2013
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4LL9
| Crystal structure of D3D4 domain of the LILRB1 molecule | Descriptor: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | Deposit date: | 2013-07-09 | Release date: | 2013-09-11 | Last modified: | 2013-11-06 | Method: | X-RAY DIFFRACTION (2.686 Å) | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding Protein Cell, 4, 2013
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4LIQ
| Structure of the extracellular domain of human CSF-1 receptor in complex with the Fab fragment of RG7155 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment RG7155 heavy chain, Fab fragment RG7155 light chain, ... | Authors: | Benz, J, Gorr, I.H, Hertenberger, H, Ries, C.H. | Deposit date: | 2013-07-03 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy Cancer Cell, 25, 2014
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4BFI
| Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1, ... | Authors: | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | Deposit date: | 2013-03-19 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution Structure, 21, 2013
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4JM2
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4IM8
| low resolution crystal structure of mouse RAGE | Descriptor: | Advanced glycation end-products receptor | Authors: | Xu, D, Young, J.H, Krahn, J.M, Song, D, Corbett, K.D, Chazin, W.J, Pedersen, L.C, Esko, J.D. | Deposit date: | 2013-01-02 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction. Acs Chem.Biol., 8, 2013
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2M1K
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4H8W
| Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4. | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ... | Authors: | Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M. | Deposit date: | 2012-09-24 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4EXP
| Structure of mouse Interleukin-34 in complex with mouse FMS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim.Biophys.Acta, 1824, 2012
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