4N8V

Crystal structure of killer cell immunoglobulin-like receptor KIR2DS2 in complex with HLA-A

Summary for 4N8V

• Entry DOI: 10.2210/pdb4n8v/pdb
• Descriptor: Killer cell immunoglobulin-like receptor 2DS2, HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ... (5 entities in total)
• Functional Keywords: antigen presentation, cell lysing, kir binding, membrane, kir2ds2, activating kir, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P43631; Secreted: P13746; Virion membrane; Multi-pass membrane protein (Potential): P61769; Cell membrane; Single-pass type I membrane protein: Q76ZQ3
• Total number of polymer chains: 8
• Total formula weight: 133829.00

Authors

Liu, J.X.,Ren, E.C. (deposition date: 2013-10-18, release date: 2014-02-05, Last modification date: 2023-11-08)

• Primary citation: Liu, J.X.,Xiao, Z.W.,Ko, H.L.,Shen, M.X.,Ren, E.C.; Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11; Proc.Natl.Acad.Sci.USA, 111:2662-2667, 2014; PubMed: 24550293; DOI: 10.1073/pnas.1322052111

Experimental method

X-RAY DIFFRACTION (2.5 Å)