2G9A
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2G99
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1YFQ
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4ERQ
| X-ray structure of WDR5-MLL2 Win motif peptide binary complex | Descriptor: | Histone-lysine N-methyltransferase MLL2, WD repeat-containing protein 5 | Authors: | Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. | Deposit date: | 2012-04-20 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.906 Å) | Cite: | Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
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4FHL
| Nucleoporin Nup37 from Schizosaccharomyces pombe | Descriptor: | 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | Authors: | Bilokapic, S, Schwartz, T.U. | Deposit date: | 2012-06-06 | Release date: | 2012-09-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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5OV3
| Structure of the RbBP5 beta-propeller domain | Descriptor: | Retinoblastoma-binding protein 5, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | Authors: | Mittal, A, Zhang, Y, Gamblin, S.J, Wilson, J.R. | Deposit date: | 2017-08-27 | Release date: | 2018-03-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structure of the RbBP5 beta-propeller domain reveals a surface with potential nucleic acid binding sites. Nucleic Acids Res., 46, 2018
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1GXR
| WD40 Region of Human Groucho/TLE1 | Descriptor: | CALCIUM ION, TRANSDUCIN-LIKE ENHANCER PROTEIN 1 | Authors: | Pearl, L.H, Roe, S.M, Pickles, L.M. | Deposit date: | 2002-04-10 | Release date: | 2002-06-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of the C-Terminal Wd40 Repeat Domain of the Human Groucho/Tle1 Transcriptional Corepressor Structure, 10, 2002
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1ERJ
| CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1 | Descriptor: | TRANSCRIPTIONAL REPRESSOR TUP1 | Authors: | Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C. | Deposit date: | 2000-04-06 | Release date: | 2000-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast. EMBO J., 19, 2000
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4XFV
| Crystal Structure of Elp2 | Descriptor: | Elongator complex protein 2 | Authors: | Lin, Z, Dong, C, Long, J, Shen, Y. | Deposit date: | 2014-12-29 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The elp2 subunit is essential for elongator complex assembly and functional regulation Structure, 23, 2015
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1PGU
| YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), Se-Met PROTEIN, MONOCLINIC CRYSTAL FORM | Descriptor: | Actin interacting protein 1, ZINC ION | Authors: | Voegtli, W.C, Madrona, A.Y, Wilson, D.K. | Deposit date: | 2003-05-28 | Release date: | 2003-07-15 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization. J.Biol.Chem., 278, 2003
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1PI6
| YEAST ACTIN INTERACTING PROTEIN 1 (Aip1), ORTHORHOMBIC CRYSTAL FORM | Descriptor: | Actin interacting protein 1, ZINC ION | Authors: | Voegtli, W.C, Madrona, A.Y, Wilson, D.K. | Deposit date: | 2003-05-29 | Release date: | 2003-07-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization. J.Biol.Chem., 278, 2003
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2CE9
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2CNX
| WDR5 and Histone H3 Lysine 4 dimethyl complex at 2.1 angstrom | Descriptor: | HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5 | Authors: | Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-25 | Release date: | 2006-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13, 2006
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2CO0
| WDR5 and unmodified Histone H3 complex at 2.25 Angstrom | Descriptor: | HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5 | Authors: | Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-25 | Release date: | 2006-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13, 2006
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2CE8
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1NR0
| Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans Homologue Of Yeast Actin Interacting Protein 1 (AIP1). | Descriptor: | Actin interacting protein 1, MANGANESE (II) ION | Authors: | Vorobiev, S.M, Mohri, K, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-01-23 | Release date: | 2003-07-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification of Functional Residues on Caenorhabditis elegans Actin-interacting Protein 1 (UNC-78) for Disassembly of Actin Depolymerizing Factor/Cofilin-bound Actin Filaments J.Biol.Chem., 279, 2004
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5SXM
| WDR5 in complex with MLL Win motif peptidomimetic | Descriptor: | ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5 | Authors: | Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S. | Deposit date: | 2016-08-09 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes. J.Biol.Chem., 291, 2016
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1PEV
| Crystal Structure of the Actin Interacting Protein from Caenorhabditis Elegans | Descriptor: | Actin interacting protein 1 | Authors: | Vorobiev, S, Mohri, K, Fedorov, A.A, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-05-22 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments. J.Biol.Chem., 279, 2004
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1U4C
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1TRJ
| Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome | Descriptor: | Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA | Authors: | Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J. | Deposit date: | 2004-06-21 | Release date: | 2004-09-28 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM Nat.Struct.Mol.Biol., 11, 2004
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1S4U
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1R5M
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1SQ9
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3PSL
| Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic | Descriptor: | N-alpha acetylated form of histone H3, WD repeat-containing protein 5 | Authors: | Avdic, V, Zhang, P, Lanouette, S, Voronova, A, Skerjanc, I, Couture, J.-F. | Deposit date: | 2010-12-01 | Release date: | 2010-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic. Faseb J., 25, 2011
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3RFG
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