2CE9
A WRPW peptide bound to the Groucho-TLE WD40 domain.
Summary for 2CE9
Entry DOI | 10.2210/pdb2ce9/pdb |
Related | 1GXR 2CE8 |
Descriptor | TRANSDUCIN-LIKE ENHANCER PROTEIN 1, WRPW PEPTIDE (3 entities in total) |
Functional Keywords | transcriptional co-repressor, wd40 domain, wnt signaling pathway, nuclear protein, phosphorylation, repressor, transcription, transcription regulation, wd repeat |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 6 |
Total formula weight | 148965.75 |
Authors | Pickles, L.M.,Roe, S.M.,Pearl, L.H. (deposition date: 2006-02-03, release date: 2006-06-14, Last modification date: 2023-12-13) |
Primary citation | Jennings, B.H.,Pickles, L.M.,Wainwright, S.M.,Roe, S.M.,Pearl, L.H.,Ish-Horowicz, D. Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor. Mol.Cell, 22:645-, 2006 Cited by PubMed: 16762837DOI: 10.1016/J.MOLCEL.2006.04.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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