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6DHS
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BU of 6dhs by Molmil
Structure of hnRNP H qRRM1,2
Descriptor: Heterogeneous nuclear ribonucleoprotein H
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2018-05-21
Release date:2018-09-12
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
6DBP
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BU of 6dbp by Molmil
RNA-recognition motif 1 of human MSI2
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Goldgur, Y, Kharas, M.G, Minuesa, G.
Deposit date:2018-05-03
Release date:2019-05-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nat Commun, 10, 2019
6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XLX
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BU of 6xlx by Molmil
Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
6XLV
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BU of 6xlv by Molmil
Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
7CSX
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BU of 7csx by Molmil
Crystal structure of the N-terminal tandem RRM domains of RBM45
Descriptor: RNA-binding protein 45
Authors:Chen, X, Yang, Z, Wang, W, Wang, M.
Deposit date:2020-08-17
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
7D1L
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BU of 7d1l by Molmil
complex structure of two RRM domains
Descriptor: Embryonic developmental protein tofu-6, Uncharacterized protein
Authors:Wang, X, Liao, S, Xu, C.
Deposit date:2020-09-14
Release date:2021-08-25
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
7DLZ
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BU of 7dlz by Molmil
Crystal Structure of Methyltransferase Ribozyme
Descriptor: RNA (45-MER), U1 small nuclear ribonucleoprotein A
Authors:Gan, J.H, Gao, Y.Q, Jiang, H.Y, Chen, D.R, Murchie, A.I.H.
Deposit date:2020-11-30
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences
Nat Catal, 4, 2021
5UZG
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BU of 5uzg by Molmil
Crystal structure of Glorund qRRM1 domain
Descriptor: AT27789p, GLYCEROL, SULFATE ION
Authors:Teramoto, T, Hall, T.M.T.
Deposit date:2017-02-26
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition.
Cell Rep, 19, 2017
5UZM
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Crystal structure of Glorund qRRM2 domain
Descriptor: AT27789p
Authors:Teramoto, T, Hall, T.M.T.
Deposit date:2017-02-27
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition.
Cell Rep, 19, 2017
6HIP
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BU of 6hip by Molmil
Structure of SPF45 UHM bound to HIV-1 Rev ULM
Descriptor: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ...
Authors:Pabis, M, Corsini, L, Sattler, M.
Deposit date:2018-08-30
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
Nucleic Acids Res., 47, 2019
7DWH
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BU of 7dwh by Molmil
Complex structure of SAM-dependent methyltransferase ribozyme
Descriptor: COPPER (II) ION, RNA (45-MER), S-ADENOSYLMETHIONINE, ...
Authors:Jiang, H.Y, Gao, Y.Q, Chen, D.R, Murchie, A.
Deposit date:2021-01-17
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences
Nat Catal, 4, 2021
6JVX
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BU of 6jvx by Molmil
Crystal structure of RBM38 in complex with RNA
Descriptor: RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION
Authors:Qian, K, Li, M, Wang, J, Zhang, M, Wang, M.
Deposit date:2019-04-17
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis for mRNA recognition by human RBM38.
Biochem.J., 477, 2020
7C36
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BU of 7c36 by Molmil
c-Myc DNA binding protein structure
Descriptor: RNA-binding motif, single-stranded-interacting protein 1
Authors:Aggarwal, P, Bhavesh, N.S.
Deposit date:2020-05-11
Release date:2021-05-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter.
Nucleic Acids Res., 49, 2021
5W0G
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BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
7EB1
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BU of 7eb1 by Molmil
Solution NMR structure of the RRM domain of RNA binding protein RBM3 from homo sapiens
Descriptor: RNA-binding protein 3
Authors:Boral, S, Roy, S, Basak, A.J, Maiti, S, Lee, W, De, S.
Deposit date:2021-03-08
Release date:2021-12-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition.
Febs J., 289, 2022
5WWF
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BU of 5wwf by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
7D7V
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BU of 7d7v by Molmil
Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein
Descriptor: 17delU1A (58-MER), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chen, H, Ren, A.M.
Deposit date:2020-10-06
Release date:2020-11-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding.
Nucleic Acids Res., 48, 2020
6JVY
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BU of 6jvy by Molmil
Crystal structure of RBM38 in complex with single-stranded DNA
Descriptor: DNA (5'-D(*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*TP*G)-3'), RNA-binding protein 38, SULFATE ION
Authors:Qian, K, Li, M, Wang, J, Zhang, M, Wang, M.
Deposit date:2019-04-17
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural basis for mRNA recognition by human RBM38.
Biochem.J., 477, 2020
5W0H
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BU of 5w0h by Molmil
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
7D2Y
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BU of 7d2y by Molmil
complex of two RRM domains
Descriptor: Embryonic developmental protein tofu-6, RRM2, SULFATE ION
Authors:Wang, X, Liao, S, Xu, C.
Deposit date:2020-09-17
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
7CSZ
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BU of 7csz by Molmil
Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA
Descriptor: DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45
Authors:Chen, X, Yang, Z, Wang, W, Wang, M.
Deposit date:2020-08-17
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
5WWE
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BU of 5wwe by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
6KOR
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BU of 6kor by Molmil
Crystal structure of the RRM domain of SYNCRIP
Descriptor: Heterogeneous nuclear ribonucleoprotein Q
Authors:Chen, Y, Chan, J, Chen, W, Jobichen, C.
Deposit date:2019-08-12
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020
5WWG
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BU of 5wwg by Molmil
Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018

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数据于2024-06-12公开中

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