5W0H
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Summary for 5W0H
| Entry DOI | 10.2210/pdb5w0h/pdb |
| Related | 5W0G |
| Descriptor | Splicing factor U2AF 65 kDa subunit (2 entities in total) |
| Functional Keywords | rna splicing factor, rna recognition motif, polypyrimidine tract, rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus: P26368 |
| Total number of polymer chains | 1 |
| Total formula weight | 8966.24 |
| Authors | Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2017-05-30, release date: 2018-04-11, Last modification date: 2023-10-04) |
| Primary citation | Glasser, E.,Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56:4757-4761, 2017 Cited by PubMed: 28850223DOI: 10.1021/acs.biochem.7b00551 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.11 Å) |
Structure validation
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