5W0G

Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution

Summary for 5W0G

• Entry DOI: 10.2210/pdb5w0g/pdb
• Related: 2HZC
• Descriptor: Splicing factor U2AF 65 kDa subunit, ZINC ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: rna splicing factor, rna recognition motif, rrm, polypyrimidine tract, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus: P26368
• Total number of polymer chains: 1
• Total formula weight: 10072.16

Authors

Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2017-05-30, release date: 2018-04-11, Last modification date: 2023-10-04)

• Primary citation: Glasser, E.,Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L.; Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.; Biochemistry, 56:4757-4761, 2017; PubMed: 28850223; DOI: 10.1021/acs.biochem.7b00551

Experimental method

X-RAY DIFFRACTION (1.07 Å)