2HZC

Crystal structure of the N-terminal RRM of the U2AF large subunit

Replaces:  2FZR

Summary for 2HZC

• Entry DOI: 10.2210/pdb2hzc/pdb
• Related: 2G4B
• Descriptor: Splicing factor U2AF 65 kDa subunit, ZINC ION, HEXAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: rna splicing, rrm, rna recognition, alternative conformation, rna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P26368
• Total number of polymer chains: 1
• Total formula weight: 10043.14

Authors

Thickman, K.R.,Sickmier, E.A.,Kielkopf, C.L. (deposition date: 2006-08-08, release date: 2006-08-29, Last modification date: 2024-02-21)

• Primary citation: Thickman, K.R.,Sickmier, E.A.,Kielkopf, C.L.; Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif.; J.Mol.Biol., 366:703-710, 2007; PubMed: 17188295; DOI: 10.1016/j.jmb.2006.11.077

Experimental method

X-RAY DIFFRACTION (1.47 Å)