1AT0
| 17-kDA fragment of hedgehog C-terminal autoprocessing domain | Descriptor: | 17-HEDGEHOG | Authors: | Hall, T.M.T, Porter, J.A, Young, K.E, Koonin, E.V, Beachy, P.A, Leahy, D.J. | Deposit date: | 1997-08-15 | Release date: | 1997-11-12 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell(Cambridge,Mass.), 91, 1997
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1VHH
| A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG | Descriptor: | SONIC HEDGEHOG, SULFATE ION, ZINC ION | Authors: | Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J. | Deposit date: | 1995-10-03 | Release date: | 1996-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog. Nature, 378, 1995
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4WZW
| Crystal structure of human Puf-A in complex with DNA | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), Pumilio domain-containing protein KIAA0020 | Authors: | Qiu, C, Hall, T.M.T. | Deposit date: | 2014-11-20 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9516 Å) | Cite: | A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization. Proc.Natl.Acad.Sci.USA, 111, 2014
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6LVR
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7LWZ
| Apo Structure of Vibrio cholerae dGTPase protein VC1979 | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1, NICKEL (II) ION | Authors: | Sikkema, A.P, Horng, J, Klemm, B.P, Schaaper, R.M, Hall, T.M.T. | Deposit date: | 2021-03-02 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structure of Vibrio cholerae dGTPase protein VC1979 To Be Published
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1RPU
| Crystal Structure of CIRV p19 bound to siRNA | Descriptor: | 19 kDa protein, 5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*UP*CP*AP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3' | Authors: | Vargason, J.M, Szittya, G, Burgyan, J, Hall, T.M.T. | Deposit date: | 2003-12-03 | Release date: | 2004-01-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Size selective recognition of siRNA by an RNA silencing suppressor Cell(Cambridge,Mass.), 115, 2003
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8SCH
| TCEI_III NMR Structure | Descriptor: | RNA (68-MER) | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | Deposit date: | 2023-04-05 | Release date: | 2023-07-12 | Last modified: | 2023-09-20 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos. Nucleic Acids Res., 51, 2023
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8SCF
| TCEIII NMR Structure | Descriptor: | RNA (30-MER) | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | Deposit date: | 2023-04-05 | Release date: | 2023-07-12 | Last modified: | 2023-09-20 | Method: | SOLUTION NMR | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos. Nucleic Acids Res., 51, 2023
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8SJ7
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1M8W
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA | Descriptor: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*CP*CP*AP*G)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', ... | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8Y
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE2-10 RNA | Descriptor: | 5'-R(P*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3', Pumilio 1 | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8X
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA | Descriptor: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', Pumilio 1 | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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6PUN
| Crystal structure of a ternary complex of FBF-2 with LST-1 (site B) and compact FBE RNA | Descriptor: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, GLYCEROL, ... | Authors: | Qiu, C, Campbell, Z.T, Hall, T.M.T. | Deposit date: | 2019-07-18 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity. Elife, 8, 2019
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4DZS
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7S02
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7RZZ
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6WPI
| Crystal structure of Nop9 in complex with ITS1 RNA | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Nucleolar protein 9, ... | Authors: | Zhang, J, Qiu, C, Hall, T.M.T. | Deposit date: | 2020-04-27 | Release date: | 2020-05-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA. Rna, 26, 2020
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4WZR
| Crystal structure of human Puf-A | Descriptor: | GLYCEROL, Pumilio domain-containing protein KIAA0020 | Authors: | Qiu, C, Hall, T.M.T. | Deposit date: | 2014-11-20 | Release date: | 2014-12-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.154 Å) | Cite: | A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization. Proc.Natl.Acad.Sci.USA, 111, 2014
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3BX2
| Puf4 RNA binding domain bound to HO endonuclease RNA 3' UTR recognition sequence | Descriptor: | HO endonuclease 3' UTR binding sequence, Protein PUF4, SODIUM ION, ... | Authors: | Miller, M.T, Higgin, J.J, Hall, T.M.T. | Deposit date: | 2008-01-11 | Release date: | 2008-03-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p Nat.Struct.Mol.Biol., 15, 2008
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3BX3
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3BWT
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2YJY
| A specific and modular binding code for cytosine recognition in PUF domains | Descriptor: | 5'-R(*AP*UP*UP*GP*CP*AP*UP*AP*UP*AP)-3', PUMILIO HOMOLOG 1 | Authors: | Dong, S, Wang, Y, Cassidy-Amstutz, C, Lu, G, Qiu, C, Bigler, R, Jezyk, M, Li, C, Hall, T.M.T, Wang, Z. | Deposit date: | 2011-05-24 | Release date: | 2011-06-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Specific and Modular Binding Code for Cytosine Recognition in Pumilio/Fbf (Puf) RNA-Binding Domains. J.Biol.Chem., 286, 2011
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1M8Z
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7TU3
| Structure of the L. blandensis dGTPase del55-58 mutant | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ... | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU2
| Structure of the L. blandensis dGTPase R37A mutant bound to Mn | Descriptor: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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