PDB: 259 件ウェブページステータス検索Chemie searchBIRD

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6U3G	Best fitting antiparallel model for Volume 2 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399) 分子名称: Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Das, S, Lambright, D.G. 登録日 2019-08-21 公開日 2019-09-25 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (53 Å) 主引用文献 Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure, 27, 2019
6D8Z	Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio 分子名称: Triple functional domain protein 著者 Bandekar, S, Tesmer, J.J. 登録日 2018-04-27 公開日 2019-02-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential. Sci Signal, 12, 2019
6DLU	Cryo-EM of the GMPPCP-bound human dynamin-1 polymer assembled on the membrane in the constricted state 分子名称: Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER 著者 Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. 登録日 2018-06-02 公開日 2018-08-01 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
3KSY	Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS) 分子名称: Son of sevenless homolog 1 著者 Gureasko, J, Kuchment, O, Kuriyan, J. 登録日 2009-11-24 公開日 2010-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.178 Å) 主引用文献 Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc.Natl.Acad.Sci.USA, 107, 2010
6DLV	Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state 分子名称: Dynamin-1 著者 Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. 登録日 2018-06-02 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (10.1 Å) 主引用文献 Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
1RJ2	Crystal structure of the DH/PH fragment of Dbs without bound GTPase 分子名称: Guanine nucleotide exchange factor DBS [Fragment] 著者 Worthylake, D.K, Rossman, K.L, Sondek, J. 登録日 2003-11-18 公開日 2004-06-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the DH/PH fragment of Dbs without bound GTPase. Structure, 12, 2004
6E31	Crystal structure of RIAM in an autoinhibited configuration. 分子名称: Rap1-interacting adapter molecule 著者 Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J. 登録日 2018-07-12 公開日 2019-02-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3LJU	Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3 分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, ZINC ION 著者 Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-01-26 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107, 2010
3MDB	Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, Kinesin-like protein KIF13B, ... 著者 Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-03-30 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.952 Å) 主引用文献 Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 to be published
3MPX	Crystal structure of the DH and PH-1 domains of human FGD5 分子名称: FYVE, RhoGEF and PH domain-containing protein 5, UNKNOWN ATOM OR ION 著者 Shen, Y, Nedyalkova, L, Tong, Y, Tempel, W, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-04-27 公開日 2010-06-23 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the DH and PH-1 domains of human FGD5 TO BE PUBLISHED
4GMV	Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin 分子名称: Ras-associated and pleckstrin homology domains-containing protein 1 著者 Chang, Y.C.E, Wu, J. 登録日 2012-08-16 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
4GN1	Crystal Structure of the RA and PH domains of Lamellipodin 分子名称: MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1 著者 Chang, Y.C.E, Wu, J. 登録日 2012-08-16 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
3TCA	Crystal structure of the Ras-associating and pleckstrin-homology domains of RIAM 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein 著者 Wu, J, Hubbard, S.R. 登録日 2011-08-08 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector. J.Cell Biol., 199, 2012
4GZU	Crystal structure of the DH-PH-PH domain of FARP2 分子名称: FERM, RhoGEF and pleckstrin domain-containing protein 2 著者 He, X, Zhang, X. 登録日 2012-09-06 公開日 2013-03-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2. Structure, 21, 2013
4H6Y	Crystal structure of the DH-PH-PH domain of FARP1 分子名称: FERM, RhoGEF and pleckstrin domain-containing protein 1 著者 He, X, Zhang, X. 登録日 2012-09-19 公開日 2013-03-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.09 Å) 主引用文献 Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2. Structure, 21, 2013
4H8S	Crystal structure of human APPL2BARPH domain 分子名称: DCC-interacting protein 13-beta 著者 Martin, J.L, King, G.J. 登録日 2012-09-23 公開日 2012-10-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase. J.Biol.Chem., 287, 2012
4K2O	The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain 分子名称: T-lymphoma invasion and metastasis-inducing protein 1 著者 Joshi, M, Gakhar, L, Fuentes, E.J. 登録日 2013-04-09 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 High-resolution structure of the Tiam1 PHn-CC-Ex domain. Acta Crystallogr.,Sect.F, 69, 2013
4K2P	The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain 分子名称: CALCIUM ION, T-lymphoma invasion and metastasis-inducing protein 1 著者 Joshi, M, Gakhar, L, Fuentes, E.J. 登録日 2013-04-09 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 High-resolution structure of the Tiam1 PHn-CC-Ex domain. Acta Crystallogr.,Sect.F, 69, 2013
3ZVR	Crystal structure of Dynamin 分子名称: DYNAMIN-1, PENTAETHYLENE GLYCOL 著者 Ford, M.G.J, Jenni, S, Nunnari, J. 登録日 2011-07-27 公開日 2011-09-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Crystal Structure of Dynamin Nature, 477, 2011
3ZYS	Human dynamin 1 deltaPRD polymer stabilized with GMPPCP 分子名称: DYNAMIN-1, INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 著者 Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F. 登録日 2011-08-24 公開日 2011-10-12 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (12.2 Å) 主引用文献 A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke. Cell(Cambridge,Mass.), 147, 2011
2Q13	Crystal structure of BAR-PH domain of APPL1 分子名称: DCC-interacting protein 13 alpha 著者 Zhu, G, Zhang, X.C. 登録日 2007-05-23 公開日 2007-08-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. Embo J., 26, 2007
2R09	Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... 著者 DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G. 登録日 2007-08-17 公開日 2007-12-04 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors. Mol.Cell, 28, 2007
2R0D	Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor 分子名称: Cytohesin-3, DI(HYDROXYETHYL)ETHER, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... 著者 DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G. 登録日 2007-08-18 公開日 2007-12-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors. Mol.Cell, 28, 2007
2Z0O	Crystal structure of APPL1-BAR-PH domain 分子名称: DCC-interacting protein 13-alpha 著者 Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-07 公開日 2008-05-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of APPL1-BAR-PH domain To be Published
2Z0P	Crystal structure of PH domain of Bruton's tyrosine kinase 分子名称: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Tyrosine-protein kinase BTK, ZINC ION 著者 Murayama, K, Kato-Murayama, M, Mishima, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-07 公開日 2008-05-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol Biochem.Biophys.Res.Commun., 377, 2008

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