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5TXK
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BU of 5txk by Molmil
CRYSTAL STRUCTURE OF USP35 C450S IN COMPLEX WITH UBIQUITIN
分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, SULFATE ION, ...
著者Bader, G, Weiss-Puxbaum, A, Zoephel, A.
登録日2016-11-17
公開日2018-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Expansion of DUB functionality generated by alternative isoforms - USP35, a case study.
J. Cell. Sci., 131, 2018
5MPC
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BU of 5mpc by Molmil
26S proteasome in presence of BeFx (s4)
分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
著者Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E.
登録日2016-12-16
公開日2017-03-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OHP
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BU of 5ohp by Molmil
Crystal structure of USP30 (C77A) in complex with Lys6-linked diubiquitin
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION
著者Gersch, M, Komander, D.
登録日2017-07-17
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
5OHK
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BU of 5ohk by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (high resolution)
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ...
著者Gersch, M, Komander, D.
登録日2017-07-17
公開日2017-09-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
5OHN
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BU of 5ohn by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (low resolution)
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION
著者Gersch, M, Komander, D.
登録日2017-07-17
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
6JLQ
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BU of 6jlq by Molmil
Crystal structure of human USP46-WDR48-WDR20 complex
分子名称: GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ...
著者Zhu, H, Zhang, T, Ding, J.
登録日2019-03-06
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
6HEK
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BU of 6hek by Molmil
Structure of human USP28 bound to Ubiquitin-PA
分子名称: CHLORIDE ION, Polyubiquitin-B, TETRAETHYLENE GLYCOL, ...
著者Gersch, M, Komander, D.
登録日2018-08-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEI
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BU of 6hei by Molmil
Structure of the catalytic domain of USP28 (insertion deleted) bound to Ubiquitin-PA
分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28
著者Gersch, M, Komander, D.
登録日2018-08-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6H4H
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BU of 6h4h by Molmil
Usp28 catalytic domain variant E593D in complex with UbPA
分子名称: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 28, ...
著者Klemm, T.A, Sauer, F, Kisker, C.
登録日2018-07-21
公開日2019-03-27
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities.
Mol.Cell, 74, 2019
5JTJ
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BU of 5jtj by Molmil
USP7CD-CTP in complex with Ubiquitin
分子名称: CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
5JTV
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BU of 5jtv by Molmil
USP7CD-UBL45 in complex with Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.312 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
5K1A
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BU of 5k1a by Molmil
Crystal structure of the UAF1-USP12 complex in C2 space group
分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5K1C
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BU of 5k1c by Molmil
Crystal structure of the UAF1/WDR20/USP12 complex
分子名称: PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ...
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5K1B
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BU of 5k1b by Molmil
Crystal structure of the UAF1/USP12 complex in F222 space group
分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5L8W
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BU of 5l8w by Molmil
Structure of USP12-UB-PRG/UAF1
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ...
著者Dharadhar, S, Sixma, T.
登録日2016-06-08
公開日2016-09-28
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
5KYC
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BU of 5kyc by Molmil
Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin (malonate bound)
分子名称: GLYCEROL, MALONIC ACID, Polyubiquitin-B, ...
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.426 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
5KYF
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BU of 5kyf by Molmil
Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
5KYE
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BU of 5kye by Molmil
Crystal structure of USP7 catalytic domain [H294E] mutant in complex with ubiquitin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
5L8H
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BU of 5l8h by Molmil
Structure of USP46-UbVME
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
著者Clerici, M, Sixma, T, Dharadhar, S.
登録日2016-06-07
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
5KYD
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BU of 5kyd by Molmil
Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
8QZS
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BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-29
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QP8
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BU of 8qp8 by Molmil
Cryo-EM Structure of Pre-B Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-30
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8R0B
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BU of 8r0b by Molmil
Cryo-EM structure of the cross-exon pre-B+ATP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QPK
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BU of 8qpk by Molmil
Cryo-EM Structure of Pre-B+5'ss Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-02
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QPE
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BU of 8qpe by Molmil
Cryo-EM Structure of Pre-B-like Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024

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