7UL5
 
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7UL2
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7UL3
 | | CryoEM Structure of Inactive H2R Bound to Famotidine, Nb6M, and NabFab | | 分子名称: | Histamine H2 receptor, NabFab HC, NabFab LC, ... | | 著者 | Robertson, M.J, Skiniotis, G. | | 登録日 | 2022-04-03 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure determination of inactive-state GPCRs with a universal nanobody.
Nat.Struct.Mol.Biol., 29, 2022
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7UL4
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7VV0
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7VV6
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80 (local) | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Mas-related G-protein coupled receptor member X2 | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7WC5
 | | Crystal structure of serotonin 2A receptor in complex with psilocin | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-ol, 5-hydroxytryptamine receptor 2A, ... | | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | | 登録日 | 2021-12-18 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs.
Science, 375, 2022
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7WC4
 | | Crystal structure of serotonin 2A receptor in complex with serotonin | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, CHOLESTEROL, ... | | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | | 登録日 | 2021-12-18 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs.
Science, 375, 2022
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1U19
 | | Crystal Structure of Bovine Rhodopsin at 2.2 Angstroms Resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Okada, T, Sugihara, M, Bondar, A.N, Elstner, M, Entel, P, Buss, V. | | 登録日 | 2004-07-15 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure
J.Mol.Biol., 342, 2004
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2G87
 | | Crystallographic model of bathorhodopsin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Nakamichi, H, Okada, T. | | 登録日 | 2006-03-02 | | 公開日 | 2006-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallographic analysis of primary visual photochemistry
Angew.Chem.Int.Ed.Engl., 45, 2006
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1JFP
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1F88
 | | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RETINAL, ... | | 著者 | Okada, T, Palczewski, K, Stenkamp, R.E, Miyano, M. | | 登録日 | 2000-06-29 | | 公開日 | 2000-08-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of rhodopsin: A G protein-coupled receptor.
Science, 289, 2000
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1L9H
 | | Crystal structure of bovine rhodopsin at 2.6 angstroms RESOLUTION | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Okada, T, Fujiyoshi, Y, Silow, M, Navarro, J, Landau, E.M, Shichida, Y. | | 登録日 | 2002-03-23 | | 公開日 | 2002-05-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1LN6
 | | STRUCTURE OF BOVINE RHODOPSIN (Metarhodopsin II) | | 分子名称: | RETINAL, RHODOPSIN | | 著者 | Choi, G, Landin, J, Galan, J.F, Birge, R.R, Albert, A.D, Yeagle, P.L. | | 登録日 | 2002-05-03 | | 公開日 | 2002-07-10 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural studies of metarhodopsin II, the activated form of the G-protein coupled receptor, rhodopsin.
Biochemistry, 41, 2002
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1GZM
 | | Structure of Bovine Rhodopsin in a Trigonal Crystal Form | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | 著者 | Li, J. | | 登録日 | 2002-05-24 | | 公開日 | 2003-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of Bovine Rhodopsin in a Trigonal Crystal Form
J.Mol.Biol., 343, 2004
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1HZX
 | | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Teller, D.C, Okada, T, Behnke, C.A, Palczewski, K, Stenkamp, R.E. | | 登録日 | 2001-01-26 | | 公開日 | 2001-07-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Biochemistry, 40, 2001
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2PED
 | | Crystallographic model of 9-cis-rhodopsin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Nakamichi, H, Okada, T. | | 登録日 | 2007-04-02 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography
Biophys.J., 92, 2007
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2RH1
 | | High resolution crystal structure of human B2-adrenergic G protein-coupled receptor. | | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ... | | 著者 | Cherezov, V, Rosenbaum, D.M, Hanson, M.A, Rasmussen, S.G.F, Thian, F.S, Kobilka, T.S, Choi, H.J, Kuhn, P, Weis, W.I, Kobilka, B.K, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | | 登録日 | 2007-10-05 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318, 2007
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7M8W
 | | XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with 15R-methyl-PGD2 | | 分子名称: | 15R-methyl-prostaglandin D2, CITRATE ANION, Prostaglandin D2 receptor 2, ... | | 著者 | Shiriaeva, A, Han, G.W, Cherezov, V. | | 登録日 | 2021-03-30 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Molecular basis for lipid recognition by the prostaglandin D 2 receptor CRTH2.
Proc.Natl.Acad.Sci.USA, 118, 2021
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3C9L
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3C9M
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3CAP
 | | Crystal Structure of Native Opsin: the G Protein-Coupled Receptor Rhodopsin in its Ligand-free State | | 分子名称: | 2-O-octyl-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | 著者 | Park, J.H, Scheerer, P, Hofmann, K.P, Choe, H.-W, Ernst, O.P. | | 登録日 | 2008-02-20 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the ligand-free G-protein-coupled receptor opsin
Nature, 454, 2008
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4X1H
 | | Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... | | 著者 | Blankenship, E, Lodowski, D.T. | | 登録日 | 2014-11-24 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.
Structure, 23, 2015
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7NA8
 | | Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | | 分子名称: | 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine], Antibody fragment, CHOLESTEROL, ... | | 著者 | Liu, H, Sun, D, Sun, J, Zhang, C. | | 登録日 | 2021-06-20 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
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7NA7
 | | Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | | 分子名称: | Antibody fragment, CHOLESTEROL, Ghrelin-27, ... | | 著者 | Liu, H, Sun, D, Sun, J, Zhang, C. | | 登録日 | 2021-06-20 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
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