PDB: 123 件ウェブページステータス検索Chemie searchBIRD

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5FWV	Wnt modulator Kremen crystal form III at 3.2A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, KREMEN PROTEIN 1 著者 Zebisch, M, Jackson, V.A, Jones, E.Y. 登録日 2016-02-21 公開日 2016-07-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf Structure, 24, 2016
6LZ9	t8E4 antibody Fab complexed with the active form of HGF 分子名称: Heavy chain of t8E4 Fab fragment, Hepatocyte growth factor, Light chain of t8E4 Fab fragment 著者 Kitago, Y, Umitsu, M, Takagi, J. 登録日 2020-02-18 公開日 2020-03-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 t8E4 antibody Fab complexed with the active form of HGF To Be Published
6UZ4	Solution structure of AGL55-Kringle 2 complex 分子名称: M protein, Plasminogen 著者 Qiu, C, Yuan, Y, Castellino, F.J. 登録日 2019-11-14 公開日 2020-12-09 実験手法 SOLUTION NMR 主引用文献 Structural evolution of the A-domain in plasminogen-binding Group A streptococcal M-protein reflects improved adaptability of the pathogen to the host To Be Published
6SNW	Structure of Coxsackievirus A10 complexed with its receptor KREMEN1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP3, ... 著者 Zhao, Y, Zhou, D, Ni, T, Karia, D, Kotecha, A, Wang, X, Rao, Z, Jones, E.Y, Fry, E.E, Ren, J, Stuart, D.I. 登録日 2019-08-27 公開日 2020-01-15 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10. Nat Commun, 11, 2020
6UZ5	Solution structure of KTI55-Kringle 2 complex 分子名称: M protein, Plasminogen 著者 Qiu, C, Yuan, Y, Castellino, F.J. 登録日 2019-11-14 公開日 2020-12-09 実験手法 SOLUTION NMR 主引用文献 Structural evolution of the A-domain in plasminogen-binding Group A streptococcal M-protein reflects improved adaptability of the pathogen to the host To Be Published
4NZQ	Crystal structure of Ca2+-free prothrombin deletion mutant residues 146-167 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin 著者 Pozzi, N, Chen, Z, Shropshire, D.B, Pelc, L.A, Di Cera, E. 登録日 2013-12-12 公開日 2014-05-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 The linker connecting the two kringles plays a key role in prothrombin activation. Proc.Natl.Acad.Sci.USA, 111, 2014
4O03	Crystal structure of Ca2+ bound prothrombin deletion mutant residues 146-167 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Prothrombin 著者 Pozzi, N, Chen, Z, Shropshire, D.B, Pelc, L.A, Di Cera, E. 登録日 2013-12-13 公開日 2014-05-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 The linker connecting the two kringles plays a key role in prothrombin activation. Proc.Natl.Acad.Sci.USA, 111, 2014
8UF7	Cryo-EM structure of POmAb, a Type-I anti-prothrombin antiphospholipid antibody, bound to kringle-1 of human prothrombin 分子名称: POmAb Heavy Chain, POmAb Light Chain, Prothrombin 著者 Kumar, S, Summers, B, Basore, K, Pozzi, N. 登録日 2023-10-03 公開日 2024-02-14 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure and functional basis of prothrombin recognition by a type I antiprothrombin antiphospholipid antibody. Blood, 143, 2024
7BZT	Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ... 著者 Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. 登録日 2020-04-28 公開日 2020-07-22 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
7BZU	Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ... 著者 Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. 登録日 2020-04-28 公開日 2020-07-22 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
3K65	Crystal Structure of Prethombin-2/Fragment-2 Complex 分子名称: 1,4-BUTANEDIOL, Prothrombin 著者 Adams, T.E, Huntington, J.A. 登録日 2009-10-08 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural transitions during prothrombin activation: On the importance of fragment 2. Biochimie, 122, 2016
5FWW	Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4) 分子名称: CALCIUM ION, DICKKOPF-RELATED PROTEIN 1, KREMEN PROTEIN 1, ... 著者 Zebisch, M, Jackson, V.A, Jones, E.Y. 登録日 2016-02-21 公開日 2016-07-20 最終更新日 2016-09-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf Structure, 24, 2016
5FWS	Wnt modulator Kremen crystal form I at 1.90A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, KREMEN PROTEIN 1, ... 著者 Zebisch, M, Jackson, V.A, Jones, E.Y. 登録日 2016-02-21 公開日 2016-07-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf Structure, 24, 2016
2PF2	THE CA+2 ION AND MEMBRANE BINDING STRUCTURE OF THE GLA DOMAIN OF CA-PROTHROMBIN FRAGMENT 1 分子名称: CALCIUM ION, PROTHROMBIN FRAGMENT 1 著者 Soriano-Garcia, M, Padmanabhan, K, De vos, A.M, Tulinsky, A. 登録日 1991-12-08 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1. Biochemistry, 31, 1992
3NXP	Crystal structure of human prethrombin-1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Chen, Z, Bush-Pelc, L.A, Di Cera, E. 登録日 2010-07-14 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of prethrombin-1. Proc.Natl.Acad.Sci.USA, 107, 2010
2PF1	STRUCTURE OF BOVINE PROTHROMBIN FRAGMENT 1 REFINED AT 2.25 ANGSTROMS RESOLUTION 分子名称: PROTHROMBIN FRAGMENT 1 著者 Seshadri, T.P, Tulinsky, A, Skrzypczak-Jankun, E, Park, C.H. 登録日 1992-09-17 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of bovine prothrombin fragment 1 refined at 2.25 A resolution. J.Mol.Biol., 220, 1991
2DOI	The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM 分子名称: Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM 著者 Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H. 登録日 2006-04-29 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM Biochemistry, 45, 2006
2DOH	The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM 分子名称: 1,4-DIETHYLENE DIOXIDE, Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM 著者 Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H. 登録日 2006-04-29 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM Biochemistry, 45, 2006
6BJR	Crystal structure of prothrombin mutant S101C/A470C 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... 著者 Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. 登録日 2017-11-06 公開日 2018-06-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Structure of prothrombin in the closed form reveals new details on the mechanism of activation. Sci Rep, 8, 2018
6C2W	Crystal structure of human prothrombin mutant S101C/A470C 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... 著者 Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. 登録日 2018-01-09 公開日 2018-02-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (4.12 Å) 主引用文献 Structure of prothrombin in the closed form reveals new details on the mechanism of activation. Sci Rep, 8, 2018
1A0H	THE X-RAY CRYSTAL STRUCTURE OF PPACK-MEIZOTHROMBIN DESF1: KRINGLE/THROMBIN AND CARBOHYDRATE/KRINGLE/THROMBIN INTERACTIONS AND LOCATION OF THE LINKER CHAIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, MEIZOTHROMBIN 著者 Martin, P.D, Malkowski, M.G, Box, J, Esmon, C.T, Edwards, B.F.P. 登録日 1997-11-30 公開日 1998-06-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK. Structure, 5, 1997
6OQK	SOLUTION STRUCTURE OF THE COMPLEX OF MUTANT VEK50[RH2/AA] AND PLASMINOGEN KRINGLE 2 分子名称: Plasminogen Kringle 2, Plasminogen-binding group A streptococcal M-like protein PAM 著者 Yuan, Y, Castellino, F.J. 登録日 2019-04-26 公開日 2019-07-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes. J.Struct.Biol., 208, 2019
6OQJ	SOLUTION STRUCTURE OF THE COMPLEX OF MUTANT VEK50[RH1/AA] AND PLASMINOGEN KRINGLE 2 分子名称: Plasminogen kringle 2, Plasminogen-binding group A streptococcal M-like protein PAM 著者 Yuan, Y, Castellino, F.J. 登録日 2019-04-26 公開日 2019-07-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes. J.Struct.Biol., 208, 2019
6PX5	CRYSTAL STRUCTURE OF HUMAN MEIZOTHROMBIN DESF1 MUTANT S195A bound with PPACK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Prothrombin, ... 著者 Pelc, L.A, Koester, S.K, Chen, Z, Gistover, N, Di Cera, E. 登録日 2019-07-24 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Residues W215, E217 and E192 control the allosteric E*-E equilibrium of thrombin. Sci Rep, 9, 2019
2HPQ	Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin 分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ... 著者 Tulinsky, A, Padmanabhan, K. 登録日 1993-04-28 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin. Biochemistry, 32, 1993

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