3K65

Crystal Structure of Prethombin-2/Fragment-2 Complex

Summary for 3K65

• Entry DOI: 10.2210/pdb3k65/pdb
• Related: 1HAG 2HPQ 3E6P
• Descriptor: Prothrombin, 1,4-BUTANEDIOL, ... (4 entities in total)
• Functional Keywords: prothrombin, coagulation, zymogen, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 2
• Total formula weight: 48191.22

Authors

Adams, T.E.,Huntington, J.A. (deposition date: 2009-10-08, release date: 2010-09-29, Last modification date: 2023-09-06)

• Primary citation: Adams, T.E.,Huntington, J.A.; Structural transitions during prothrombin activation: On the importance of fragment 2.; Biochimie, 122:235-242, 2016; PubMed: 26365066; DOI: 10.1016/j.biochi.2015.09.013

Experimental method

X-RAY DIFFRACTION (1.85 Å)