PDB: 2435 件ウェブページステータス検索Chemie searchBIRD

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4CI8	Crystal structure of the tandem atypical beta-propeller domain of EML1 分子名称: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1, SULFATE ION 著者 Richards, M.W, Bayliss, R. 登録日 2013-12-06 公開日 2014-04-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Eml1 Reveals the Basis for Hsp90 Dependence of Oncogenic Eml4-Alk by Disruption of an Atypical Beta-Propeller Domain. Proc.Natl.Acad.Sci.USA, 111, 2014
5A9Q	Human nuclear pore complex 分子名称: NUCLEAR PORE COMPLEX PROTEIN NUP107, NUCLEAR PORE COMPLEX PROTEIN NUP133, NUCLEAR PORE COMPLEX PROTEIN NUP155, ... 著者 von Appen, A, Kosinski, J, Sparks, L, Ori, A, DiGuilio, A, Vollmer, B, Mackmull, M, Banterle, N, Parca, L, Kastritis, P, Buczak, K, Mosalaganti, S, Hagen, W, Andres-Pons, A, Lemke, E.A, Bork, P, Antonin, W, Glavy, J.S, Bui, K.H, Beck, M. 登録日 2015-07-22 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (23 Å) 主引用文献 In Situ Structural Analysis of the Human Nuclear Pore Complex Nature, 526, 2015
4BL0	Crystal structure of yeast Bub3-Bub1 bound to phospho-Spc105 分子名称: CELL CYCLE ARREST PROTEIN BUB3, CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, MAGNESIUM ION, ... 著者 Primorac, I, Weir, J.R, Musacchio, A. 登録日 2013-04-30 公開日 2013-09-18 最終更新日 2013-10-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Bub3 Reads Phosphorylated Melt Repeats to Promote Spindle Assembly Checkpoint Signaling Elife, 2, 2013
4E5Z	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair 分子名称: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... 著者 Yeh, J.I, Du, S. 登録日 2012-03-15 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
5BJS	Apo ctPRC2 in an autoinhibited state 分子名称: Histone-lysine N-methyltransferase EZH2, Polycomb protein SUZ12, Polycomb Protein EED, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2016-10-22 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Polycomb repressive complex 2 in an autoinhibited state. J. Biol. Chem., 292, 2017
4E54	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair 分子名称: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... 著者 Yeh, J.I, Du, S. 登録日 2012-03-14 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
5C9Z	Crystal structure of PRMT5:MEP50 with EPZ015866 and sinefungin 分子名称: 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]pyridine-4-carboxamide, GLYCEROL, Methylosome protein 50, ... 著者 Boriack-Sjodin, P.A. 登録日 2015-06-29 公開日 2016-06-29 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of PRMT5/MEP50 complex with sinefungin and 15866 To Be Published
5CXC	Structure of Ytm1 bound to the C-terminal domain of Erb1 in P 65 2 2 space group 分子名称: CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 著者 Wegrecki, M, Bravo, J. 登録日 2015-07-28 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5CYK	Structure of Ytm1 bound to the C-terminal domain of Erb1-R486E 分子名称: CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 著者 Wegrecki, M, Bravo, J. 登録日 2015-07-30 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5EM2	Crystal structure of the Erb1-Ytm1 complex 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ribosome biogenesis protein ERB1, ... 著者 Ahmed, Y.L, Sinning, I. 登録日 2015-11-05 公開日 2015-12-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interface. Nucleic Acids Res., 44, 2016
5EMM	Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
5CVL	WDR48 (UAF-1), residues 2-580 分子名称: GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48 著者 HARRIS, S.F, YIN, J. 登録日 2015-07-27 公開日 2015-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
5EML	Crystal structure of PRMT5:MEP50 with Compound 10 and SAM 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
5EMK	Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
5CXB	Structure of Ytm1 bound to the C-terminal domain of Erb1 in P21 21 2 space group 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Wegrecki, M, Bravo, J. 登録日 2015-07-28 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5EMJ	Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin 分子名称: (2~{S})-1-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-3-[[4-(3-methylbenzimidazol-5-yl)pyridin-2-yl]amino]propan-2-ol, GLYCEROL, Methylosome protein 50, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.273 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
3W15	Structure of peroxisomal targeting signal 2 (PTS2) of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase in complex with Pex7p and Pex21p 分子名称: 3-ketoacyl-CoA thiolase, peroxisomal, Maltose-binding periplasmic protein, ... 著者 Pan, D, Nakatsu, T, Kato, H. 登録日 2012-11-06 公開日 2013-07-03 最終更新日 2017-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p Nat.Struct.Mol.Biol., 20, 2013
3V7D	Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex 分子名称: Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1 著者 Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M. 登録日 2011-12-20 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 109, 2012
4AEZ	Crystal Structure of Mitotic Checkpoint Complex 分子名称: MITOTIC SPINDLE CHECKPOINT COMPONENT MAD2, MITOTIC SPINDLE CHECKPOINT COMPONENT MAD3, WD REPEAT-CONTAINING PROTEIN SLP1 著者 Kulkarni, K.A, Chao, W.C.H, Zhang, Z, Barford, D. 登録日 2012-01-13 公開日 2012-03-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Mitotic Checkpoint Complex Nature, 484, 2012
4A0B	Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.8 A resolution (CPD 4) 分子名称: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*DGP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', DNA DAMAGE-BINDING PROTEIN 1, ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
4A0L	Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex 分子名称: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ... 著者 Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. 登録日 2011-09-09 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (7.4 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
4A0A	Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.6 A resolution (CPD 3) 分子名称: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', CALCIUM ION, ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
4A0K	STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX 分子名称: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ... 著者 Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. 登録日 2011-09-09 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (5.93 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
4A08	Structure of hsDDB1-drDDB2 bound to a 13 bp CPD-duplex (purine at D-1 position) at 3.0 A resolution (CPD 1) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*CP*GP*CP*GP*AP*(TTD)P*GP*CP*GP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*CP*GP*CP*CP*CP*TP*CP*GP*CP*G)-3', ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
4A09	Structure of hsDDB1-drDDB2 bound to a 15 bp CPD-duplex (purine at D-1 position) at 3.1 A resolution (CPD 2) 分子名称: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*GP)-3', CALCIUM ION, ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011

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