PDB: 974 件ウェブページステータス検索Chemie searchBIRD

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1CEF	CEFOTAXIME COMPLEXED WITH THE STREPTOMYCES R61 DD-PEPTIDASE 分子名称: CEFOTAXIME, C3' cleaved, open, ... 著者 Knox, J.R, Kuzin, A.P. 登録日 1995-01-12 公開日 1996-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
1CI9	DFP-INHIBITED ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI 分子名称: DIISOPROPYL PHOSPHONATE, PROTEIN (CARBOXYLESTERASE) 著者 Wagner, U.G, Petersen, E.I, Schwab, H, Kratky, C. 登録日 1999-04-08 公開日 2001-12-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity Protein Sci., 11, 2002
3WRT	Wild type beta-lactamase DERIVED FROM CHROMOHALOBACTER SP.560 分子名称: Beta-lactamase 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
3WS1	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-1B) 分子名称: Beta-lactamase, CALCIUM ION, CESIUM ION 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
3WS5	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-2B) 分子名称: Beta-lactamase, CALCIUM ION, CHLORIDE ION, ... 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-28 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
1CI8	ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI: AN ESTERASE WITH (BETA)-LACTAMASE FOLD. 分子名称: ISOPROPYL ALCOHOL, PROTEIN (CARBOXYLESTERASE) 著者 Wagner, U.G, Petersen, E.I, Schwab, H, Kratky, C. 登録日 1999-04-08 公開日 2001-12-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity Protein Sci., 11, 2002
3WWX	Crystal structure of D-stereospecific amidohydrolase from Streptomyces sp. 82F2 分子名称: OCTANE 1,8-DIAMINE, S12 family peptidase 著者 Arima, J, Nagano, S, Hino, T, Shimone, K, Isoda, Y, Mori, N. 登録日 2014-07-03 公開日 2015-07-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Crystal structure of D-stereospecific amidohydrolase from Streptomyces sp. 82F2 - insight into the structural factors for substrate specificity. Febs J., 283, 2016
3WS0	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-1A) 分子名称: Beta-lactamase, CALCIUM ION, CESIUM ION, ... 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
3WRZ	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (without soaking) 分子名称: Beta-lactamase, CALCIUM ION, CHLORIDE ION 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
1CEG	CEPHALOTHIN COMPLEXED WITH DD-PEPTIDASE 分子名称: CEPHALOTHIN GROUP, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRANSPEPTIDASE 著者 Knox, J.R, Kuzin, A.P. 登録日 1995-01-12 公開日 1996-10-14 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
3ZYT	Structure Determination of EstA from Arthrobacter nitroguajacolicus Rue61a 分子名称: ESTERASE A, ETHYL MERCURY ION 著者 Wagner, U.G, Fetzner, S. 登録日 2011-08-25 公開日 2012-09-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure Analysis of Esta from Arthrobacter Sp. Rue61A--an Insight Into Catalytic Promiscuity. FEBS Lett., 588, 2014
3WS4	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-2A) 分子名称: Beta-lactamase, CHLORIDE ION, STRONTIUM ION 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-28 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
1C3B	AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB) 分子名称: BENZO[B]THIOPHENE-2-BORONIC ACID, CEPHALOSPORINASE 著者 Powers, R.A, Blazquez, J, Weston, G.S, Morosini, M.I, Baquero, F, Shoichet, B.K. 登録日 1999-07-27 公開日 1999-11-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The complexed structure and antimicrobial activity of a non-beta-lactam inhibitor of AmpC beta-lactamase. Protein Sci., 8, 1999
3WS2	N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-1C) 分子名称: Beta-lactamase, CALCIUM ION, CESIUM ION 著者 Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
3W8K	Crystal structure of class C beta-lactamase Mox-1 分子名称: ACETATE ION, Beta-lactamase, ZINC ION 著者 Shimizu-ibuka, A, Oguri, T, Furuyama, T, Ishii, Y. 登録日 2013-03-15 公開日 2014-04-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Mox-1, a unique plasmid-mediated class C beta-lactamase with hydrolytic activity towards moxalactam Antimicrob.Agents Chemother., 58, 2014
1BSG	BETA-LACTAMASE FROM STREPTOMYCES ALBUS G 分子名称: ACETATE ION, BETA LACTAMASE 著者 Fonze, E, Charlier, P, Dideberg, O. 登録日 1998-07-20 公開日 1999-01-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献
3VWL	Crystal structure of 6-aminohexanoate-dimer hydrolase G181D/R187S/H266N/D370Y mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... 著者 Kawashima, Y, Shibata, N, Negoro, S, Higuchi, Y. 登録日 2012-08-30 公開日 2013-10-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural, kinetic and theoretical analyses of hydrolase mutants altering in the directionality and equilibrium point of reversible amide-synthetic/hydrolytic reaction To be Published
1BLS	CRYSTALLOGRAPHIC STRUCTURE OF A PHOSPHONATE DERIVATIVE OF THE ENTEROBACTER CLOACAE P99 CEPHALOSPORINASE: MECHANISTIC INTERPRETATION OF A BETA-LACTAMASE TRANSITION STATE ANALOG 分子名称: (P-IODOPHENYLACETYLAMINO)METHYLPHOSPHINIC ACID, BETA-LACTAMASE 著者 Knox, J.R, Moews, P.C, Lobkovsky, E. 登録日 1993-12-17 公開日 1995-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog. Biochemistry, 33, 1994
3GV9	AmpC beta-lactamase in complex with Fragment-based Inhibitor 分子名称: 3-(acetylamino)thiophene-2-carboxylic acid, Beta-lactamase, DI(HYDROXYETHYL)ETHER, ... 著者 Teotico, D.T, Shoichet, B.K. 登録日 2009-03-30 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3GRJ	AmpC beta-lactamase in complex with Fragment-based Inhibitor 分子名称: 2-phenyl-1H-imidazole-4-carboxylic acid, Beta-lactamase, DI(HYDROXYETHYL)ETHER, ... 著者 Teotico, D.T, Shoichet, B.K. 登録日 2009-03-25 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3GQZ	AmpC beta-lactamase in complex with Fragment-based Inhibitor 分子名称: (3S)-1-(4-acetylphenyl)-5-oxopyrrolidine-3-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE 著者 Teotico, D.T, Shoichet, B.K. 登録日 2009-03-24 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3GTC	AmpC beta-lactamase in complex with Fragment-based Inhibitor 分子名称: (1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Teotico, D.T, Shoichet, B.K. 登録日 2009-03-27 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3HLC	Simvastatin Synthase (LovD) from Aspergillus terreus, S5 mutant, unliganded 分子名称: GLYCEROL, TETRAETHYLENE GLYCOL, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLD	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant complex with monacolin J acid 分子名称: (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, FORMIC ACID, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLG	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with lovastatin 分子名称: (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009

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