3GRJ

AmpC beta-lactamase in complex with Fragment-based Inhibitor

Summary for 3GRJ

Entry DOI	10.2210/pdb3grj/pdb
Related	3GQZ 3GR2 3GSG 3GTC 3GV9 3GVB
Descriptor	Beta-lactamase, PHOSPHATE ION, 2-phenyl-1H-imidazole-4-carboxylic acid, ... (6 entities in total)
Functional Keywords	hydrolase/hydrolase inhibitor, antibiotic resistance, hydrolase, periplasm, hydrolase-hydrolase inhibitor complex
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	80862.98
Authors	Teotico, D.T.,Shoichet, B.K. (deposition date: 2009-03-25, release date: 2009-04-14, Last modification date: 2023-09-06)
Primary citation	Teotico, D.G.,Babaoglu, K.,Rocklin, G.J.,Ferreira, R.S.,Giannetti, A.M.,Shoichet, B.K. Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106:7455-7460, 2009 Cited by PubMed: 19416920 DOI: 10.1073/pnas.0813029106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation