PDB: 898 resultsInfo pagesStatus searchChemie searchBIRD

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4Y00	Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA Descriptor: DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 Authors: Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. Deposit date: 2015-02-05 Release date: 2016-02-10 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
5EV1	Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.037 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV2	Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.86 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV3	Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3'), Splicing factor U2AF 65 kDa subunit Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV4	Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, Splicing factor U2AF 65 kDa subunit Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.57 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
2N82	solution structure of the complex of microRNA 20b pre-element with Rbfox RRM Descriptor: RNA (5'-R(*GP*GP*UP*AP*GP*UP*UP*UP*UP*GP*GP*CP*AP*UP*GP*AP*CP*UP*CP*UP*AP*CP*C)-3'), RNA binding protein fox-1 homolog 1 Authors: Yang, F, Chen, Y, Varani, G. Deposit date: 2015-09-30 Release date: 2016-04-13 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer. Nucleic Acids Res., 44, 2016
5IQQ	Crystal structure of the human RBM7 RRM domain Descriptor: RNA-binding protein 7 Authors: Sofos, N, Winkler, M.B.L, Brodersen, D.E. Deposit date: 2016-03-11 Release date: 2016-05-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.52 Å) Cite: RRM domain of human RBM7: purification, crystallization and structure determination. Acta Crystallogr.,Sect.F, 72, 2016
5FJ4	Structure of the standard kink turn HmKt-7 as stem loop bound with U1A and L7Ae proteins Descriptor: 50S RIBOSOMAL PROTEIN L7AE, HMKT-7, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A Authors: Huang, L, Lilley, D.M.J. Deposit date: 2015-10-06 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.95 Å) Cite: A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
3JCT	Cryo-em structure of eukaryotic pre-60S ribosomal subunits Descriptor: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... Authors: Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. Deposit date: 2016-03-09 Release date: 2016-06-01 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
4ZKA	High Resolution Crystal Structure of Fox1 RRM Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RNA binding protein fox-1 homolog 1, SULFATE ION, ... Authors: Blatter, M, Allain, F.H.-T. Deposit date: 2015-04-30 Release date: 2016-06-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: High Resolution Crystal Structure of Fox1 RRM To Be Published
5K1H	eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. Descriptor: Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail Authors: Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. Deposit date: 2016-05-18 Release date: 2016-07-13 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
5K0Y	m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face Descriptor: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... Authors: Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. Deposit date: 2016-05-17 Release date: 2016-07-13 Last modified: 2018-04-18 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
2N3L	Solution structure of RNA recognition motif-1 of Plasmodium falciparum serine/arginine-rich protein 1. Descriptor: serine/arginine-rich protein 1, PfSR1-RRM1 Authors: Ganguly, A, Verma, G, Bhavesh, N.S. Deposit date: 2015-06-05 Release date: 2016-07-20 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The N-terminal RNA Recognition Motif of PfSR1 Confers Semi-specificity for Pyrimidines during RNA Recognition. J. Mol. Biol., 431, 2019
5LJ3	Structure of the core of the yeast spliceosome immediately after branching Descriptor: CEF1, CLF1, CWC15, ... Authors: Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. Deposit date: 2016-07-17 Release date: 2016-08-03 Last modified: 2019-10-23 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
5IM0	Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1 Descriptor: Heterogeneous nuclear ribonucleoprotein D0 Authors: Choi, Y.J, Chang, J.H. Deposit date: 2016-03-05 Release date: 2016-08-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1. Biomed Res Int, 2016, 2016
5D78	Structure of RRM3 Domain of Mip6 at 1.25 A Resolution Descriptor: BETA-MERCAPTOETHANOL, RNA-binding protein MIP6, SULFATE ION Authors: Mohamad, N, Bravo, J. Deposit date: 2015-08-13 Release date: 2016-08-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.251 Å) Cite: Structure of RRM3 Domain of Mip6 at 1.25 A Resolution To Be Published
5GMK	Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution Descriptor: 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y. Deposit date: 2016-07-14 Release date: 2016-08-17 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution Science, 353, 2016
5D77	Structure of Mip6 RRM3 Domain Descriptor: CITRIC ACID, NITRATE ION, RNA-binding protein MIP6, ... Authors: Mohamad, N, Bravo, J. Deposit date: 2015-08-13 Release date: 2016-08-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structure of Mip6 RRM3 domain at 1.3 To Be Published
5LJ5	Overall structure of the yeast spliceosome immediately after branching. Descriptor: CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... Authors: Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. Deposit date: 2016-07-17 Release date: 2016-08-31 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
5GM6	Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. Deposit date: 2016-07-12 Release date: 2016-09-21 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of a yeast activated spliceosome at 3.5 angstrom resolution Science, 353, 2016
5LQW	yeast activated spliceosome Descriptor: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... Authors: Rauhut, R, Luehrmann, R. Deposit date: 2016-08-17 Release date: 2016-10-05 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: Molecular architecture of the Saccharomyces cerevisiae activated spliceosome Science, 6306, 2016
2N7C	Solution structure of Plasmodium falciparum SR1-RRM1 in complex with ACAUCA RNA Descriptor: RNA_(5'-R(*AP*CP*AP*UP*CP*A)-3'), putative splicing factor Authors: Ganguly, A.K, Verma, G, Bhavesh, N.S. Deposit date: 2015-09-08 Release date: 2016-10-12 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The N-terminal RNA Recognition Motif of PfSR1 Confers Semi-specificity for Pyrimidines during RNA Recognition. J. Mol. Biol., 431, 2019
5LSO	Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45 Authors: Jagtap, P.K.A, Garg, D, Sattler, M. Deposit date: 2016-09-05 Release date: 2016-10-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing. J. Med. Chem., 59, 2016
5EN1	Crystal structure of hnRNPA2B1 in complex with RNA Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') Authors: Wu, B.X, Su, S.C, Ma, J.B. Deposit date: 2015-11-09 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
5IFM	Human NONO (p54nrb) Homodimer Descriptor: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ... Authors: Knott, G.J, Bond, C.S. Deposit date: 2016-02-26 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry. Acta Crystallogr D Struct Biol, 72, 2016

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