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PDB: 161 results

2ADJ
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BU of 2adj by Molmil
Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Calcium
Descriptor: CALCIUM ION, Q425 Fab Heavy chain, Q425 Fab Light chain
Authors:Zhou, T, Hamer, D.H, Hendrickson, W.A, Sattentau, Q.J, Kwong, P.D.
Deposit date:2005-07-20
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Interfacial metal and antibody recognition.
Proc.Natl.Acad.Sci.Usa, 102, 2005
7NIP
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BU of 7nip by Molmil
titin N2A unique sequence (UN2A) core
Descriptor: Isoform 11 of Titin
Authors:Zhou, T, Kovermann, M, Fleming, J.R, Mayans, O.
Deposit date:2021-02-13
Release date:2021-03-03
Last modified:2021-03-31
Method:SOLUTION NMR
Cite:Molecular Characterisation of Titin N2A and Its Binding of CARP Reveals a Titin/Actin Cross-linking Mechanism.
J.Mol.Biol., 433, 2021
5EQY
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BU of 5eqy by Molmil
Crystal structure of choline kinase alpha-1 bound by 5-[(4-methyl-1,4-diazepan-1-yl)methyl]-2-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]benzenecarbonitrile (compound 65)
Descriptor: 5-[(4-methyl-1,4-diazepan-1-yl)methyl]-2-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]benzenecarbonitrile, Choline kinase alpha
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-13
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
5EQE
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BU of 5eqe by Molmil
Crystal structure of choline kinase alpha-1 bound by [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine (compound 11)
Descriptor: Choline kinase alpha, [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-12
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
5EQP
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BU of 5eqp by Molmil
Crystal structure of choline kinase alpha-1 bound by 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline (compound 37)
Descriptor: 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline, Choline kinase alpha
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-13
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
2NY7
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BU of 2ny7 by Molmil
HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY b12, HEAVY CHAIN, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
5VFK
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BU of 5vfk by Molmil
Solution structure of an archaeal DUF61 family protein SSO0941
Descriptor: Uncharacterized protein
Authors:Zhou, T, Wang, J, Feng, Y.
Deposit date:2017-04-07
Release date:2018-03-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of an archaeal DUF61 family protein SSO0941 encoded by a gene in the operon of box C/D RNA protein complexes.
J. Struct. Biol., 203, 2018
5WDX
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BU of 5wdx by Molmil
Structure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind and unwind viral RNA
Descriptor: JFH-1 NS3, MAGNESIUM ION, ZINC ION
Authors:Zhou, T, Pyle, A.M.
Deposit date:2017-07-06
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA.
J. Virol., 92, 2018
4PW6
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BU of 4pw6 by Molmil
structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II
Descriptor: 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2
Authors:Zhou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.789 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW5
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BU of 4pw5 by Molmil
structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I
Descriptor: 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2
Authors:ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW7
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BU of 4pw7 by Molmil
structure of UHRF2-SRA in complex with a 5mC-containing DNA
Descriptor: 5mC-containing DNA1, 5mC-containing DNA2, E3 ubiquitin-protein ligase UHRF2
Authors:ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M.
Deposit date:2014-03-19
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
8F6X
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BU of 8f6x by Molmil
cryo-EM structure of a structurally designed Human metapneumovirus F protein in complex with antibody MPE8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MPE8 Single chain variable fragment, Structurally designed HMPV F protein HMPV_v3B_D12_DS454,Fibritin
Authors:Zhou, T, Kwong, P.D, Morano, N.C, Ou, L.
Deposit date:2022-11-17
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:cryo-EM structure of a structurally designed Human metapneumovirus F protein in complex with antibody MPE8
To Be Published
5F9W
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BU of 5f9w by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ...
Authors:Chen, L, Zhou, T, Kwong, P.D.
Deposit date:2015-12-10
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8911 Å)
Cite:Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
5FYL
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BU of 5fyl by Molmil
Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 ANTIBODY FAB HEAVY CHAIN, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D.
Deposit date:2016-03-08
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G
Cell(Cambridge,Mass.), 165, 2016
5FYJ
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BU of 5fyj by Molmil
Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D.
Deposit date:2016-03-08
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G
Cell(Cambridge,Mass.), 165, 2016
5FYK
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BU of 5fyk by Molmil
Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade B JR-FL SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D.
Deposit date:2016-03-08
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.107 Å)
Cite:Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G
Cell(Cambridge,Mass.), 165, 2016
2QD0
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BU of 2qd0 by Molmil
Crystal structure of mitoNEET
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH domain-containing protein 1
Authors:Lin, J, Zhou, T, Ye, K, Wang, J.
Deposit date:2007-06-20
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1H72
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BU of 1h72 by Molmil
CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HOMOSERINE KINASE, L-HOMOSERINE, ...
Authors:Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H.
Deposit date:2001-07-02
Release date:2001-09-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1H73
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BU of 1h73 by Molmil
CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH THREONINE
Descriptor: HOMOSERINE KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, THREONINE
Authors:Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H.
Deposit date:2001-07-02
Release date:2001-09-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1H74
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BU of 1h74 by Molmil
CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, ISOLEUCINE, ...
Authors:Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H.
Deposit date:2001-07-02
Release date:2001-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
4TVP
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BU of 4tvp by Molmil
Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ...
Authors:Pancera, M, Zhou, T, Kwong, P.D.
Deposit date:2014-06-27
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Nature, 514, 2014
5M2Q
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BU of 5m2q by Molmil
Structure of cobinamide-bound BtuF mutant W66F, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-13
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5M29
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BU of 5m29 by Molmil
Structure of cobinamide-bound BtuF, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-12
Release date:2017-02-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5M3B
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BU of 5m3b by Molmil
Structure of cobinamide-bound BtuF mutant W66L, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-14
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5M34
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Structure of cobinamide-bound BtuF mutant W66Y, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-14
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017

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