2NY7

HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12

Summary for 2NY7

• Entry DOI: 10.2210/pdb2ny7/pdb
• Related: 1HZH
• Descriptor: ENVELOPE GLYCOPROTEIN GP120, ANTIBODY b12, HEAVY CHAIN, ANTIBODY b12, LIGHT CHAIN, ... (5 entities in total)
• Functional Keywords: hiv, gp120, broadly neutralizing antibody, b12, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 3
• Total formula weight: 86620.77

Authors

Zhou, T.,Xu, L.,Dey, B.,Hessell, A.J.,Van Ryk, D.,Xiang, S.H.,Yang, X.,Zhang, M.Y.,Zwick, M.B.,Arthos, J.,Burton, D.R.,Dimitrov, D.S.,Sodroski, J.,Wyatt, R.,Nabel, G.J.,Kwong, P.D. (deposition date: 2006-11-20, release date: 2007-02-06, Last modification date: 2023-08-30)

• Primary citation: Zhou, T.,Xu, L.,Dey, B.,Hessell, A.J.,Van Ryk, D.,Xiang, S.H.,Yang, X.,Zhang, M.Y.,Zwick, M.B.,Arthos, J.,Burton, D.R.,Dimitrov, D.S.,Sodroski, J.,Wyatt, R.,Nabel, G.J.,Kwong, P.D.; Structural definition of a conserved neutralization epitope on HIV-1 gp120.; Nature, 445:732-737, 2007; PubMed: 17301785; DOI: 10.1038/nature05580

Experimental method

X-RAY DIFFRACTION (2.3 Å)