1U1I
| Myo-inositol phosphate synthase mIPS from A. fulgidus | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Stieglitz, K.A, Yang, H, Roberts, M.F, Stec, B. | Deposit date: | 2004-07-15 | Release date: | 2004-08-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reaching for Mechanistic Consensus Across Life Kingdoms: Structure and Insights into Catalysis of the myo-Inositol-1-phosphate Synthase (mIPS) from Archaeoglobus fulgidus Biochemistry, 44, 2005
|
|
3IO8
| BimL12F in complex with Bcl-xL | Descriptor: | Bcl-2-like protein 1, Bcl-2-like protein 11, ZINC ION | Authors: | Colman, P.M, Lee, E.F, Fairlie, W.D, Smith, B.J, Czabotar, P.E, Yang, H, Sleebs, B.E, Lessene, G. | Deposit date: | 2009-08-14 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands. J.Biol.Chem., 284, 2009
|
|
3IO9
| BimL12Y in complex with Mcl-1 | Descriptor: | Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION | Authors: | Czabotar, P.E, Lee, E.F, Yang, H, Sleebs, B.E, Lessene, G, Colman, P.M, Smith, B.J, Fairlie, W.D. | Deposit date: | 2009-08-14 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands. J.Biol.Chem., 284, 2009
|
|
3KYS
| Crystal structure of human YAP and TEAD complex | Descriptor: | 65 kDa Yes-associated protein, Transcriptional enhancer factor TEF-1 | Authors: | Li, Z, Zhao, B, Wang, P, Chen, F, Dong, Z, Yang, H, Guan, K.L, Xu, Y. | Deposit date: | 2009-12-07 | Release date: | 2010-02-23 | Last modified: | 2020-10-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into the YAP and TEAD complex Genes Dev., 24, 2010
|
|
3R7W
| Crystal Structure of Gtr1p-Gtr2p complex | Descriptor: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | Authors: | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | Deposit date: | 2011-03-23 | Release date: | 2011-08-24 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (2.773 Å) | Cite: | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation Genes Dev., 25, 2011
|
|
3MQB
| |
3MQ7
| Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 | Descriptor: | Bone marrow stromal antigen 2, CALCIUM ION | Authors: | Xiong, Y, Yang, H, Wang, J, Meng, W. | Deposit date: | 2010-04-27 | Release date: | 2010-10-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3M0E
| Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family) | Authors: | Chen, B, Sysoeva, T.A, Chowdhury, S, Rusu, M, Birmanns, S, Guo, L, Hanson, J, Yang, H, Nixon, B.T. | Deposit date: | 2010-03-02 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Engagement of Arginine Finger to ATP Triggers Large Conformational Changes in NtrC1 AAA+ ATPase for Remodeling Bacterial RNA Polymerase. Structure, 18, 2010
|
|
3MQ9
| |
3MQC
| |
2HOB
| Crystal structure of SARS-CoV main protease with authentic N and C-termini in complex with a Michael acceptor N3 | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, Replicase polyprotein 1ab | Authors: | Xue, X, Yang, H, Shen, W, Zhao, Q, Li, J, Rao, Z. | Deposit date: | 2006-07-14 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction J.Mol.Biol., 366, 2007
|
|
4BZC
| Crystal structure of the tetrameric dGTP-bound wild type SAMHD1 catalytic core | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION, ... | Authors: | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | Deposit date: | 2013-07-25 | Release date: | 2013-10-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Mechanism of Allosteric Activation of Samhd1 by Dgtp Nat.Struct.Mol.Biol., 20, 2013
|
|
4BZB
| Crystal structure of the tetrameric dGTP-bound SAMHD1 mutant catalytic core | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION | Authors: | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | Deposit date: | 2013-07-25 | Release date: | 2013-10-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Mechanism of Allosteric Activation of Samhd1 by Dgtp Nat.Struct.Mol.Biol., 20, 2013
|
|
4FUW
| Crystal structure of Ego3 mutant | Descriptor: | Protein SLM4, SULFATE ION | Authors: | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | Deposit date: | 2012-06-28 | Release date: | 2012-11-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
|
|
4FTX
| Crystal structure of Ego3 homodimer | Descriptor: | Protein SLM4, SUCCINIC ACID | Authors: | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | Deposit date: | 2012-06-28 | Release date: | 2012-11-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
|
|
4GU0
| Crystal structure of LSD2 with H3 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3, Lysine-specific histone demethylase 1B, ... | Authors: | Chen, F, Yang, H, Dong, Z, Fang, J, Zhu, T, Gong, W, Xu, Y. | Deposit date: | 2012-08-29 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.103 Å) | Cite: | Structural insight into substrate recognition by histone demethylase LSD2/KDM1b Cell Res., 23, 2013
|
|
3U0J
| |
7A5J
| Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
7A5F
| Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
7A5H
| Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
7A5I
| Structure of the human mitoribosome with A- P-and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
7A5G
| Structure of the elongating human mitoribosome bound to mtEF-Tu.GMPPCP and A/T mt-tRNA | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
7A5K
| Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
1VE7
| Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1 in complex with p-nitrophenyl phosphate | Descriptor: | 4-NITROPHENYL PHOSPHATE, Acylamino-acid-releasing enzyme, GLYCEROL | Authors: | Bartlam, M, Wang, G, Gao, R, Yang, H, Zhao, X, Xie, G, Cao, S, Feng, Y, Rao, Z. | Deposit date: | 2004-03-27 | Release date: | 2004-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1 STRUCTURE, 12, 2004
|
|
1VE6
| Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1 | Descriptor: | Acylamino-acid-releasing enzyme, GLYCEROL, octyl beta-D-glucopyranoside | Authors: | Bartlam, M, Wang, G, Gao, R, Yang, H, Zhao, X, Xie, G, Cao, S, Feng, Y, Rao, Z. | Deposit date: | 2004-03-27 | Release date: | 2004-11-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1 STRUCTURE, 12, 2004
|
|