3ECA
 
 | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI L-ASPARAGINASE, AN ENZYME USED IN CANCER THERAPY (ELSPAR) | | Descriptor: | ASPARTIC ACID, L-asparaginase 2 | | Authors: | Swain, A.L, Jaskolski, M, Housset, D, Rao, J.K.M, Wlodawer, A. | | Deposit date: | 1993-07-02 | | Release date: | 1993-10-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.
Proc.Natl.Acad.Sci.USA, 90, 1993
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4J2Y
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6RIX
 | | Crystal structure of MchDnaB-1 intein | | Descriptor: | CHLORIDE ION, Replicative DNA helicase | | Authors: | Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H. | | Deposit date: | 2019-04-25 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.655 Å) | | Cite: | The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
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7JOS
 | | Crystal structure of BbKI complexed with Human Kallikrein 4 | | Descriptor: | Kallikrein 4 (Prostase, enamel matrix, prostate), ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-07 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
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7JR2
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7JR1
 | | Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Bovine Trypsin | | Descriptor: | Cationic trypsin, Kunitz-type inihibitor, SODIUM ION, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-11 | | Release date: | 2021-07-21 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
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7JQV
 | | Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | | Descriptor: | CHLORIDE ION, Kallikrein 4 (Prostase, enamel matrix, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-11 | | Release date: | 2021-07-21 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
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1JSR
 | | CRYSTAL STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE COMPLEXED WITH 6-HYDROXY-L-NORLEUCINE | | Descriptor: | 6-HYDROXY-L-NORLEUCINE, GLYCEROL, L-asparaginase, ... | | Authors: | Aghaiypour, K, Wlodawer, A, Lubkowski, J. | | Deposit date: | 2001-08-17 | | Release date: | 2002-01-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
Biochim.Biophys.Acta, 1550, 2001
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1JSL
 | | Crystal structure of Erwinia chrysanthemi L-asparaginase complexed with 6-HYDROXY-D-NORLEUCINE | | Descriptor: | 6-HYDROXY-D-NORLEUCINE, GLYCEROL, L-asparaginase, ... | | Authors: | Aghaiypour, K, Wlodawer, A, Lubkowski, J. | | Deposit date: | 2001-08-17 | | Release date: | 2002-01-09 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
Biochim.Biophys.Acta, 1550, 2001
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6RIZ
 | | Crystal structure of gp41-1 intein (C1A, F65W, D107C) | | Descriptor: | gp41-1 intein | | Authors: | Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H. | | Deposit date: | 2019-04-25 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
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4KHT
 | | Triple helix bundle of GP41 complexed with fab 8066 | | Descriptor: | 8066 heavy chain, 8066 light chain, Gp41 helix | | Authors: | Li, M, Gustchina, A, Wlodawer, A. | | Deposit date: | 2013-05-01 | | Release date: | 2014-03-12 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.817 Å) | | Cite: | Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
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6RIY
 | | Crystal structure of MchDnaB-1 intein (N145AA) | | Descriptor: | CHLORIDE ION, Replicative DNA helicase | | Authors: | Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H. | | Deposit date: | 2019-04-25 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
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4KHX
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7JQO
 | | Crystal structure of the R64D mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-11 | | Release date: | 2021-07-21 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
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7JQN
 | | Crystal structure of the R64M mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-11 | | Release date: | 2021-07-21 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
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7JQK
 | | Crystal structure of the R64A mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-11 | | Release date: | 2021-07-21 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
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4MON
 | | ORTHORHOMBIC MONELLIN | | Descriptor: | MONELLIN | | Authors: | Bujacz, G, Wlodawer, A. | | Deposit date: | 1997-03-04 | | Release date: | 1997-07-07 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of monellin refined to 2.3 a resolution in the orthorhombic crystal form.
Acta Crystallogr.,Sect.D, 53, 1997
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6PAE
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6QAZ
 | | Crystal structure of gp41-1 intein | | Descriptor: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | | Authors: | Mikula, K.M, Beyer, H.M, Li, M, Wlodawer, A, Iwai, H. | | Deposit date: | 2018-12-20 | | Release date: | 2019-11-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.02 Å) | | Cite: | The crystal structure of the naturally split gp41-1 intein guides the engineering of orthogonal split inteins from cis-splicing inteins.
Febs J., 287, 2020
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2ITG
 | | CATALYTIC DOMAIN OF HIV-1 INTEGRASE: ORDERED ACTIVE SITE IN THE F185H CONSTRUCT | | Descriptor: | HUMAN IMMUNODEFICIENCY VIRUS-1 INTEGRASE | | Authors: | Bujacz, G, Alexandratos, J, Wlodawer, A, Zhou-Liu, Q, Clement-Mella, C. | | Deposit date: | 1996-09-13 | | Release date: | 1997-03-12 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant.
FEBS Lett., 398, 1996
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6N2I
 | | Lon protease AAA+ domain | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA-binding ATP-dependent protease La | | Authors: | Botos, I, Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2018-11-13 | | Release date: | 2019-07-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | New insights into structural and functional relationships between LonA proteases and ClpB chaperones.
Febs Open Bio, 9, 2019
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7JOD
 | | Crytsal structure of BbKI complexed with Human Kallikrein 4 | | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-06 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
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7JOW
 | | Crystal structure of BbKI complexed with Human Kallikrein 4 | | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-07 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
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7JOE
 | | Crystal structure of BbKI complexed with Human Kallikrein 4 | | Descriptor: | Kallikrein 4 (Prostase, enamel matrix, prostate), ... | | Authors: | Li, M, Wlodawer, A, Gustchina, A. | | Deposit date: | 2020-08-06 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
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6NXD
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