1QU0
 
 | | CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN | | Descriptor: | CALCIUM ION, LAMININ ALPHA2 CHAIN, SULFATE ION | | Authors: | Hohenester, E, Tisi, D, Talts, J.F, Timpl, R. | | Deposit date: | 1999-07-05 | | Release date: | 1999-12-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.
Mol.Cell, 4, 1999
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1H4U
 | | Domain G2 of mouse nidogen-1 | | Descriptor: | NIDOGEN-1 | | Authors: | Hopf, M, Gohring, W, Ries, A, Timpl, R, Hohenester, E. | | Deposit date: | 2001-05-14 | | Release date: | 2001-06-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1
Nat.Struct.Biol., 8, 2001
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1H30
 | | C-terminal LG domain pair of human Gas6 | | Descriptor: | CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION | | Authors: | Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E. | | Deposit date: | 2002-08-21 | | Release date: | 2003-01-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
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2C5D
 | | Structure of a minimal Gas6-Axl complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | | Deposit date: | 2005-10-26 | | Release date: | 2005-12-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
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1KLO
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1BMO
 | | BM-40, FS/EC DOMAIN PAIR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BM-40, CALCIUM ION | | Authors: | Hohenester, E, Maurer, P, Timpl, R. | | Deposit date: | 1997-03-25 | | Release date: | 1997-10-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.
EMBO J., 16, 1997
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1OKQ
 | | LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT | | Descriptor: | CALCIUM ION, LAMININ ALPHA 2 CHAIN | | Authors: | Wizemann, H, Garbe, J.H.O, Friedrich, M.V.K, Timpl, R, Sasaki, T, Hohenester, E. | | Deposit date: | 2003-07-28 | | Release date: | 2003-09-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Distinct Requirements for Heparin and Alpha-Dystroglycan Binding Revealed by Structure-Based Mutagenesis of the Laminin Alpha2 Lg4-Lg5 Domain Pair
J.Mol.Biol., 332, 2003
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1TLE
 | | LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES | | Descriptor: | LAMININ | | Authors: | Baumgartner, R, Czisch, M, Mayer, U, Schl, E.P, Huber, R, Timpl, R, Holak, T.A. | | Deposit date: | 1996-01-26 | | Release date: | 1997-02-12 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structure of the nidogen binding LE module of the laminin gamma1 chain in solution.
J.Mol.Biol., 257, 1996
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1BNL
 | | ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN | | Descriptor: | COLLAGEN XVIII, ZINC ION | | Authors: | Ding, Y.-H, Javaherian, K, Lo, K.-M, Chopra, R, Boehm, T, Lanciotti, J, Harris, B.A, Li, Y, Shapiro, R, Hohenester, E, Timpl, R, Folkman, J, Wiley, D.C. | | Deposit date: | 1998-07-30 | | Release date: | 1998-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Zinc-dependent dimers observed in crystals of human endostatin.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1BY2
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1NUB
 | | HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BASEMENT MEMBRANE PROTEIN BM-40, CALCIUM ION | | Authors: | Hohenester, E, Sasaki, T, Timpl, R. | | Deposit date: | 1997-12-05 | | Release date: | 1998-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.
EMBO J., 17, 1998
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1LI1
 | | The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link | | Descriptor: | ACETATE ION, Collagen alpha 1(IV), Collagen alpha 2(IV) | | Authors: | Than, M.E, Henrich, S, Huber, R, Ries, A, Mann, K, Kuhn, K, Timpl, R, Bourenkov, G.P, Bartunik, H.D, Bode, W. | | Deposit date: | 2002-04-17 | | Release date: | 2002-05-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1SRA
 | | STRUCTURE OF A NOVEL EXTRACELLULAR CA2+-BINDING MODULE IN BM-40(SLASH)SPARC(SLASH)OSTEONECTIN | | Descriptor: | CALCIUM ION, SPARC | | Authors: | Hohenester, E, Maurer, P, Hohenadl, C, Timpl, R, Jansonius, J.N, Engel, J. | | Deposit date: | 1995-08-21 | | Release date: | 1996-03-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a novel extracellular Ca(2+)-binding module in BM-40.
Nat.Struct.Biol., 3, 1996
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1GL4
 | | Nidogen-1 G2/Perlecan IG3 Complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, NIDOGEN-1, ... | | Authors: | Kvansakul, M, Hopf, M, Ries, A, Timpl, R, Hohenester, E. | | Deposit date: | 2001-08-23 | | Release date: | 2001-11-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan
Embo J., 20, 2001
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1KOE
 | | ENDOSTATIN | | Descriptor: | ENDOSTATIN | | Authors: | Hohenester, E, Sasaki, T, Olsen, B.R, Timpl, R. | | Deposit date: | 1998-01-22 | | Release date: | 1999-02-16 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution.
EMBO J., 17, 1998
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1DY0
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1DY2
 | | Murine collagen alpha1(XV), endostatin domain | | Descriptor: | COLLAGEN ALPHA1(XV) CHAIN, SULFATE ION | | Authors: | Tisi, D, Hohenester, E, Sasaki, T, Timpl, R. | | Deposit date: | 2000-01-21 | | Release date: | 2001-01-21 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Endostatin Derived from Collagens Xv and Xviii Differ in Structural and Binding Properties, Tissue Distribution and Anti-Angiogenic Activity
J.Mol.Biol., 301, 2000
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1DY1
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1DYK
 | | Laminin alpha 2 chain LG4-5 domain pair | | Descriptor: | CALCIUM ION, LAMININ ALPHA 2 CHAIN | | Authors: | Tisi, D, Talts, J.F, Timple, R, Hohenester, E. | | Deposit date: | 2000-02-01 | | Release date: | 2001-02-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the C-Terminal Laminin G-Like Domain Pair of the Laminin Alpha 2 Chain Harbouring Binding Sites for Alpha-Dystroglycan and Heparin
Embo J., 19, 2000
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