5TWX
 
 | | Crystal Structure of BRD9 bromodomain | | Descriptor: | Bromodomain-containing protein 9, N-[6-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)hexyl]-2-(4-{2-[N-(1,1-dioxo-1lambda~6~-thian-4-yl)carbamimidoyl]-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridin-7-yl}-2-methoxyphenoxy)acetamide | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2016-11-15 | | Release date: | 2017-09-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
Angew. Chem. Int. Ed. Engl., 56, 2017
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7SZD
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7SZC
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7SZB
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7SZA
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7U5W
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7U5X
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5WHH
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5VS6
 | | Structure of DUB complex | | Descriptor: | ACETATE ION, GLYCEROL, N-[3-({4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl}methyl)-4-oxo-3,4-dihydroquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide, ... | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2017-05-11 | | Release date: | 2017-12-20 | | Last modified: | 2018-01-03 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
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5VSK
 | | Structure of DUB complex | | Descriptor: | 7-chloro-3-({4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | | Authors: | Seo, H.-Y, Dhe-Paganon, S. | | Deposit date: | 2017-05-11 | | Release date: | 2017-12-20 | | Last modified: | 2018-01-03 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
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5VSB
 | | Structure of DUB complex | | Descriptor: | 7-chloro-3-{[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl}quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7 | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2017-05-11 | | Release date: | 2017-12-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
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7S7G
 | | Crystal Structure Analysis of Human VLCAD | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2021-09-15 | | Release date: | 2022-09-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Crystal Structure Analysis of Human VLCAD
To Be Published
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7TUN
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7TUO
 | | Crystal structure analysis of human USP28 complex with a compound | | Descriptor: | 7-amino-N-(2-{4-[(1R,3s,5S)-8-azabicyclo[3.2.1]octan-3-yl]phenyl}ethyl)-3-methylthieno[2,3-b]pyrazine-6-carboxamide, CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 28 | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2022-02-03 | | Release date: | 2023-02-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Crystal Structure Analysis of human USP28 complex with a compound
To Be Published
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6MBZ
 | | Structure of Transcription Factor | | Descriptor: | Signal transducer and activator of transcription 5B | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2018-08-30 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Structural and functional consequences of the STAT5BN642Hdriver mutation.
Nat Commun, 10, 2019
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6MBW
 | | Structure of Transcription Factor | | Descriptor: | Signal transducer and activator of transcription 5B | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2018-08-30 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Structural and functional consequences of the STAT5BN642H driver mutation.
Nat Commun, 10, 2019
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8EBK
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5ITS
 | | Crystal structure of LOG from Corynebacterium glutamicum | | Descriptor: | Cytokinin riboside 5'-monophosphate phosphoribohydrolase, GLYCEROL, PHOSPHATE ION | | Authors: | Seo, H.-G, Kim, K.-J. | | Deposit date: | 2016-03-17 | | Release date: | 2016-08-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for cytokinin production by LOG from Corynebacterium glutamicum
Sci Rep, 6, 2016
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7DG5
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5WHI
 | | Crystal Structure of Bcl-2-related protein A1 | | Descriptor: | Bcl-2-related protein A1, CACODYLIC ACID | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2017-07-17 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Structure, 26, 2018
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5TVT
 | | Structure of Maternal Embryonic Leucine Zipper Kinase | | Descriptor: | 9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3-methyl-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one, Maternal embryonic leucine zipper kinase | | Authors: | Seo, H.-Y, Huang, H, Gray, N.S, Dhe-Paganon, S. | | Deposit date: | 2016-11-10 | | Release date: | 2017-11-15 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structure of Maternal Embryonic Leucine Zipper Kinase
To Be Published
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5WQ3
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7DIB
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3F7F
 | | Structure of Nup120 | | Descriptor: | MERCURY (II) ION, Nucleoporin NUP120 | | Authors: | Seo, H.S, Ma, Y, Debler, E.W, Blobel, G, Hoelz, A. | | Deposit date: | 2008-11-08 | | Release date: | 2009-08-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex.
Proc.Natl.Acad.Sci.USA, 106, 2009
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6ISS
 | | Lignin peroxidase H8 triple mutant S49C/A67C/H239 | | Descriptor: | CALCIUM ION, Ligninase H8, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Seo, H, Son, H, Kim, K.-J. | | Deposit date: | 2018-11-19 | | Release date: | 2019-11-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Extra disulfide and ionic salt bridge improves the thermostability of lignin peroxidase H8 under acidic condition
Enzyme.Microb.Technol., 148, 2021
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