6MBW

Structure of Transcription Factor

Summary for 6MBW

Entry DOI	10.2210/pdb6mbw/pdb
Descriptor	Signal transducer and activator of transcription 5B (2 entities in total)
Functional Keywords	transcription factor, transcription activator
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	131238.75
Authors	Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2018-08-30, release date: 2019-06-19, Last modification date: 2023-10-11)
Primary citation	de Araujo, E.D.,Erdogan, F.,Neubauer, H.A.,Meneksedag-Erol, D.,Manaswiyoungkul, P.,Eram, M.S.,Seo, H.S.,Qadree, A.K.,Israelian, J.,Orlova, A.,Suske, T.,Pham, H.T.T.,Boersma, A.,Tangermann, S.,Kenner, L.,Rulicke, T.,Dong, A.,Ravichandran, M.,Brown, P.J.,Audette, G.F.,Rauscher, S.,Dhe-Paganon, S.,Moriggl, R.,Gunning, P.T. Structural and functional consequences of the STAT5BN642H driver mutation. Nat Commun, 10:2517-2517, 2019 Cited by PubMed: 31175292 DOI: 10.1038/s41467-019-10422-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.29 Å)

Structure validation