7S7G
Crystal Structure Analysis of Human VLCAD
Summary for 7S7G
Entry DOI | 10.2210/pdb7s7g/pdb |
Descriptor | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | dehydrogenase, mitochondrial acyl-coa dehydrogenases, flavin adenine dinucleotide, deficiency, fatty acid oxidation, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 67611.99 |
Authors | Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2021-09-15, release date: 2022-09-28, Last modification date: 2024-05-29) |
Primary citation | Prew, M.S.,Camara, C.M.,Botzanowski, T.,Moroco, J.A.,Bloch, N.B.,Levy, H.R.,Seo, H.S.,Dhe-Paganon, S.,Bird, G.H.,Herce, H.D.,Gygi, M.A.,Escudero, S.,Wales, T.E.,Engen, J.R.,Walensky, L.D. Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nat Commun, 13:3669-3669, 2022 Cited by PubMed: 35760926DOI: 10.1038/s41467-022-31466-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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