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PDB: 20 results

3RP2
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THE STRUCTURE OF RAT MAST CELL PROTEASE II AT 1.9-ANGSTROMS RESOLUTION
Descriptor: RAT MAST CELL PROTEASE II
Authors:Reynolds, R, Remington, S, Weaver, L, Fischer, R, Anderson, W, Ammon, H, Matthews, B.
Deposit date:1984-09-10
Release date:1984-10-29
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of rat mast cell protease II at 1.9-A resolution.
Biochemistry, 27, 1988
1I1O
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ROOM TEMPERATURE CRYSTAL STRUCTURE FLAVODOXIN D. VULGARIS MUTANT Y98H AT 2.0 ANG. RESOLUTION
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
Authors:Reynolds, R.A, Watt, W, Watenpaugh, K.D.
Deposit date:2001-02-02
Release date:2001-04-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures and comparison of the Y98H (2.0 A) and Y98W (1.5 A) mutants of flavodoxin (Desulfovibrio vulgaris).
Acta Crystallogr.,Sect.D, 57, 2001
1F4P
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Y98W FLAVODOXIN MUTANT 1.5A (D. VULGARIS)
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
Authors:Reynolds, R.A, Watt, W, Watenpaugh, K.D.
Deposit date:2000-06-08
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures and comparison of the Y98H (2.0 A) and Y98W (1.5 A) mutants of flavodoxin (Desulfovibrio vulgaris).
Acta Crystallogr.,Sect.D, 57, 2001
1RQ7
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MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH GDP
Descriptor: Cell division protein ftsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W.
Deposit date:2003-12-04
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.
J.Mol.Biol., 342, 2004
1RQ2
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MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH CITRATE
Descriptor: CITRIC ACID, Cell division protein ftsZ
Authors:Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W.
Deposit date:2003-12-04
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.
J.Mol.Biol., 342, 2004
1RLU
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Mycobacterium tuberculosis FtsZ in complex with GTP-gamma-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein ftsZ, GLYCEROL
Authors:Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W.
Deposit date:2003-11-26
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.
J.Mol.Biol., 342, 2004
2W3A
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HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND TRIMETHOPRIM
Descriptor: DIHYDROFOLATE REDUCTASE, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-10
Release date:2009-11-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
2W3W
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MYCOBACTERIUM AVIUM DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND A LIPOPHILIC ANTIFOLATE SELECTIVE FOR M. AVIUM DHFR, 6-((2,5- DIETHOXYPHENYL)AMINOMETHYL)-2,4-DIAMINO-5-METHYLPYRIDO(2,3-D) PYRIMIDINE (SRI-8686)
Descriptor: 6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-16
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
2W3B
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HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND A LIPOPHILIC ANTIFOLATE SELECTIVE FOR MYCOBACTERIUM AVIUM DHFR, 6-((2,5- DIETHOXYPHENYL)AMINOMETHYL)-2,4-DIAMINO-5-METHYLPYRIDO(2,3-D) PYRIMIDINE (SRI-8686)
Descriptor: 6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, FOLIC ACID, ...
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-11
Release date:2009-11-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
2W3M
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HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND FOLATE
Descriptor: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-13
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
2W3V
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MYCOBACTERIUM AVIUM DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND TRIMETHOPRIM
Descriptor: DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-16
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
2C2S
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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate
Descriptor: 2,4-DIAMINO-5-(1-O-CARBORANYLMETHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ...
Authors:Leung, A.K.W, Reynolds, R.C, Riordan, J.M, Borhani, D.W.
Deposit date:2005-09-29
Release date:2007-04-10
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation.
J.Med.Chem., 50, 2007
2C2T
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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-((7,8-dicarbaundecaboran-7-yl)methyl)-6-methylpyrimidine, a novel boron containing, nonclassical Antifolate
Descriptor: (S)-2,4-DIAMINO-5-((7,8-DICARBAUNDECABORAN-7-YL)METHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ...
Authors:leung, A.K.W, reynolds, R.C, riordan, J.M, borhani, D.W.
Deposit date:2005-09-30
Release date:2007-04-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation.
J.Med.Chem., 50, 2007
3P0U
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Crystal Structure of the ligand binding domain of human testicular receptor 4
Descriptor: Nuclear receptor subfamily 2 group C member 2
Authors:Zhou, X.E, Suino-Powell, K.M, Xu, Y, Chan, C.-W, Kruse, S.W, Reynolds, R, Engel, J.D, Xu, H.E.
Deposit date:2010-09-29
Release date:2010-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor.
J.Biol.Chem., 286, 2011
1QB0
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HUMAN CDC25B CATALYTIC DOMAIN
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (M-PHASE INDUCER PHOSPHATASE 2 (CDC25B)), ...
Authors:Watenpaugh, K.D, Reynolds, R.A.
Deposit date:1999-04-29
Release date:2000-04-29
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
J.Mol.Biol., 293, 1999
1XLS
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Crystal structure of the mouse CAR/RXR LBD heterodimer bound to TCPOBOP and 9cRA and a TIF2 peptide containg the third LXXLL motifs
Descriptor: (9cis)-retinoic acid, 3,5-DICHLORO-2-{4-[(3,5-DICHLOROPYRIDIN-2-YL)OXY]PHENOXY}PYRIDINE, Nuclear receptor coactivator 2, ...
Authors:Suino, K, peng, L, Reynolds, R, Li, Y, Cha, J.-Y, Repa, J.J, Kliewer, S.A, Xu, H.E.
Deposit date:2004-09-30
Release date:2004-12-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization.
Mol.Cell, 16, 2004
1CWT
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HUMAN CDC25B CATALYTIC DOMAIN WITH METHYL MERCURY
Descriptor: CDC25 B-TYPE TYROSINE PHOSPHATASE, CHLORIDE ION, METHYL MERCURY ION, ...
Authors:Watenpaugh, K.D, Reynolds, R.A.
Deposit date:1999-08-26
Release date:2000-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
J.Mol.Biol., 293, 1999
1CWS
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HUMAN CDC25B CATALYTIC DOMAIN WITH TUNGSTATE
Descriptor: BETA-MERCAPTOETHANOL, CDC25 B-TYPE TYROSINE PHOSPHATASE, CHLORIDE ION, ...
Authors:Watenpaugh, K.D, Reynolds, R.A, Chidester, C.G.
Deposit date:1999-08-26
Release date:2000-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
J.Mol.Biol., 293, 1999
1CWR
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HUMAN CDC25B CATALYTIC DOMAIN WITHOUT ION IN CATALYTIC SITE
Descriptor: BETA-MERCAPTOETHANOL, PROTEIN (M-PHASE INDUCER PHOSPHATASE 2 (CDC25B)), SULFATE ION
Authors:Watenpaugh, K.D, Reynolds, R.A, Chidester, C.G.
Deposit date:1999-08-26
Release date:2000-08-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
J.Mol.Biol., 293, 1999
3CJW
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Crystal structure of the human COUP-TFII ligand binding domain
Descriptor: COUP transcription factor 2
Authors:Kruse, S.W, Reynolds, R, Vonrhein, C, Xu, H.E.
Deposit date:2008-03-14
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid-Activated Receptor.
Plos Biol., 6, 2008

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