1QB0

HUMAN CDC25B CATALYTIC DOMAIN

Summary for 1QB0

• Entry DOI: 10.2210/pdb1qb0/pdb
• Descriptor: PROTEIN (M-PHASE INDUCER PHOSPHATASE 2 (CDC25B)), SULFATE ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: hydrolase, cell cycle phosphatase, dual specificity protein phosphatase, cdc25, cdc25b
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : P30305
• Total number of polymer chains: 1
• Total formula weight: 25291.31

Authors

Watenpaugh, K.D.,Reynolds, R.A. (deposition date: 1999-04-29, release date: 2000-04-29, Last modification date: 2018-02-28)

• Primary citation: Reynolds, R.A.,Yem, A.W.,Wolfe, C.L.,Deibel Jr., M.R.,Chidester, C.G.,Watenpaugh, K.D.; Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.; J.Mol.Biol., 293:559-568, 1999; PubMed: 10543950; DOI: 10.1006/jmbi.1999.3168

Experimental method

X-RAY DIFFRACTION (1.91 Å)