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PDB: 50 results

8DZL
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BU of 8dzl by Molmil
Structure of the K39Q mutant of rat somatic Cytochrome c at 1.36A
Descriptor: Cytochrome c, somatic, HEME C
Authors:Edwards, B.F.P, Huettemann, M, Vaishnav, A, Brunzelle, J, Morse, P, Wan, J.
Deposit date:2022-08-08
Release date:2023-07-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Nat Commun, 14, 2023
8DVX
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BU of 8dvx by Molmil
Structure of acetylated Pig somatic Cytochrome c (Aly39) at 1.5A
Descriptor: Cytochrome c, HEME C, HEXACYANOFERRATE(3-)
Authors:Edwards, B.F.P, Huettemann, M, Vaishnav, A, Brunzelle, J, Morse, P, Wan, J.
Deposit date:2022-07-30
Release date:2023-07-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Nat Commun, 14, 2023
6PNZ
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BU of 6pnz by Molmil
The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
Descriptor: Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Authors:Edwards, B.F.P, Evans, D.R, Patel, C.
Deposit date:2019-07-03
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
To Be Published
4BJH
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BU of 4bjh by Molmil
Crystal Structure of the Aquifex Reactor Complex Formed by Dihydroorotase (H180A, H232A) with Dihydroorotate and Aspartate Transcarbamoylase with N-(phosphonacetyl)-L-aspartate (PALA)
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, 1,2-ETHANEDIOL, ASPARTATE CARBAMOYLTRANSFERASE, ...
Authors:Edwards, B.F.P, Martin, P.D, Grimley, E, Vaishnav, A, Fernando, R, Brunzelle, J.S, Cordes, M, Evans, H.G, Evans, D.R.
Deposit date:2013-04-18
Release date:2013-12-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Mononuclear Metal Center of Type-I Dihydroorotase from Aquifex Aeolicus.
Bmc Biochem., 14, 2013
5C0Z
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BU of 5c0z by Molmil
The structure of oxidized rat cytochrome c at 1.13 angstroms resolution
Descriptor: Cytochrome c, somatic, HEME C, ...
Authors:Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M.
Deposit date:2015-06-12
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1236 Å)
Cite:Serine-47 phosphorylation of cytochromecin the mammalian brain regulates cytochromecoxidase and caspase-3 activity.
Faseb J., 2019
5DF5
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BU of 5df5 by Molmil
The structure of oxidized rat cytochrome c (T28E) at 1.30 angstroms resolution.
Descriptor: Cytochrome c, somatic, HEME C, ...
Authors:Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M.
Deposit date:2015-08-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.301 Å)
Cite:The structure of oxidized rat cytochrome c (T28E) at 1.30 angstroms resolution.
To Be Published
5C9M
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BU of 5c9m by Molmil
The structure of oxidized rat cytochrome c (T28A) at 1.362 angstroms resolution.
Descriptor: Cytochrome c, somatic, HEME C, ...
Authors:Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M.
Deposit date:2015-06-28
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.362 Å)
Cite:The structure of oxidized rat cytochrome c (T28A) at 1.362 angstroms resolution.
To Be Published
3D6N
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BU of 3d6n by Molmil
Crystal Structure of Aquifex Dihydroorotase Activated by Aspartate Transcarbamoylase
Descriptor: Aspartate carbamoyltransferase, CITRATE ANION, Dihydroorotase, ...
Authors:Edwards, B.F.P.
Deposit date:2008-05-20
Release date:2009-01-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dihydroorotase from the hyperthermophile Aquifiex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis.
Biochemistry, 48, 2009
1A0H
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BU of 1a0h by Molmil
THE X-RAY CRYSTAL STRUCTURE OF PPACK-MEIZOTHROMBIN DESF1: KRINGLE/THROMBIN AND CARBOHYDRATE/KRINGLE/THROMBIN INTERACTIONS AND LOCATION OF THE LINKER CHAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, MEIZOTHROMBIN
Authors:Martin, P.D, Malkowski, M.G, Box, J, Esmon, C.T, Edwards, B.F.P.
Deposit date:1997-11-30
Release date:1998-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK.
Structure, 5, 1997
1BBR
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BU of 1bbr by Molmil
THE STRUCTURE OF RESIDUES 7-16 OF THE A ALPHA CHAIN OF HUMAN FIBRINOGEN BOUND TO BOVINE THROMBIN AT 2.3 ANGSTROMS RESOLUTION
Descriptor: EPSILON-THROMBIN, FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR
Authors:Martin, P, Edwards, B.
Deposit date:1992-04-27
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution.
J.Biol.Chem., 267, 1992
1BAV
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BU of 1bav by Molmil
CARBOXYPEPTIDASE A COMPLEXED WITH 2-BENZYL-3-IODO-PROPANOIC ACID (BIP)
Descriptor: 2-BENZYL-3-IODOPROPANOIC ACID, CARBOXYPEPTIDASE A, ZINC ION
Authors:Martin, P, Edwards, B.
Deposit date:1996-11-14
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic and computational insight on the mechanism of zinc-ion-dependent inactivation of carboxypeptidase a by 2-benzyl-3-iodopropanoate.
J.Am.Chem.Soc., 118, 1996
4UU9
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BU of 4uu9 by Molmil
Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody
Descriptor: COMPLEMENT C5, MEDI7814, SULFATE ION
Authors:Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T.
Deposit date:2014-07-25
Release date:2015-08-12
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs, 10, 2018
1NAP
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BU of 1nap by Molmil
THE CRYSTAL STRUCTURE OF RECOMBINANT HUMAN NEUTROPHIL-ACTIVATING PEPTIDE-2 (M6L) AT 1.9-ANGSTROMS RESOLUTION
Descriptor: NEUTROPHIL ACTIVATING PEPTIDE-2
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1994-12-19
Release date:1995-12-19
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of recombinant human neutrophil-activating peptide-2 (M6L) at 1.9-A resolution.
J.Biol.Chem., 270, 1995
1TVX
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BU of 1tvx by Molmil
NEUTROPHIL ACTIVATING PEPTIDE-2 VARIANT FORM M6L WITH FIVE ADDITIONAL AMINO TERMINAL RESIDUES (DSDLY)
Descriptor: NEUTROPHIL ACTIVATING PEPTIDE 2 VARIANT
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1996-11-05
Release date:1997-01-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The amino-terminal residues in the crystal structure of connective tissue activating peptide-III (des10) block the ELR chemotactic sequence.
J.Mol.Biol., 266, 1997
1SSA
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BU of 1ssa by Molmil
A STRUCTURAL INVESTIGATION OF CATALYTICALLY MODIFIED F12OL AND F12OY SEMISYNTHETIC RIBONUCLEASES
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:deMel, V.S.J, Doscher, M.S, Glinn, M.A, Martin, P.D, Ram, M.L, Edwards, B.F.P.
Deposit date:1993-08-03
Release date:1994-09-30
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases.
Protein Sci., 3, 1994
1SSB
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BU of 1ssb by Molmil
A STRUCTURAL INVESTIGATION OF CATALYTICALLY MODIFIED F12OL AND F12OY SEMISYNTHETIC RIBONUCLEASES
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:Demel, V.S.J, Doscher, M.S, Glinn, M.A, Martin, P.D, Ram, M.L, Edwards, B.F.P.
Deposit date:1993-08-03
Release date:1994-09-30
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases.
Protein Sci., 3, 1994
1SSC
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BU of 1ssc by Molmil
THE 1.6 ANGSTROMS STRUCTURE OF A SEMISYNTHETIC RIBONUCLEASE CRYSTALLIZED FROM AQUEOUS ETHANOL. COMPARISON WITH CRYSTALS FROM SALT SOLUTIONS AND WITH RNASE A FROM AQUEOUS ALCOHOL SOLUTIONS
Descriptor: PHOSPHATE ION, RIBONUCLEASE A
Authors:De Mel, V.S.J, Doscher, M.S, Martin, P.D, Rodier, F, Edwards, B.F.P.
Deposit date:1994-10-05
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:1.6 A structure of semisynthetic ribonuclease crystallized from aqueous ethanol. Comparison with crystals from salt solutions and with ribonuclease A from aqueous alcohol solutions.
Acta Crystallogr.,Sect.D, 51, 1995
1PLF
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BU of 1plf by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF BOVINE PLATELET FACTOR 4 AT 3.0 ANGSTROMS RESOLUTION
Descriptor: PLATELET FACTOR 4, TETRACYANONICKELATE ION
Authors:St Charles, R, Edwards, B.F.P.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The three-dimensional structure of bovine platelet factor 4 at 3.0-A resolution.
J.Biol.Chem., 264, 1989
4SRN
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BU of 4srn by Molmil
STRUCTURAL CHANGES THAT ACCOMPANY THE REDUCED CATALYTIC EFFICIENCY OF TWO SEMISYNTHETIC RIBONUCLEASE ANALOGS
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:deMel, V.S.J, Martin, P.D, Doscher, M.S, Edwards, B.F.P.
Deposit date:1991-05-20
Release date:1994-12-20
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs.
J.Biol.Chem., 267, 1992
1MKX
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BU of 1mkx by Molmil
THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA-THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING
Descriptor: ALPHA-THROMBIN, PRETHROMBIN-2
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-03-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
Protein Sci., 6, 1997
1MKW
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BU of 1mkw by Molmil
THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA-THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING
Descriptor: ALPHA-THROMBIN, PRETHROMBIN-2
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-03-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
Protein Sci., 6, 1997
1HRT
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BU of 1hrt by Molmil
THE STRUCTURE OF A COMPLEX OF BOVINE ALPHA-THROMBIN AND RECOMBINANT HIRUDIN AT 2.8 ANGSTROMS RESOLUTION
Descriptor: HIRUDIN, THROMBIN (LARGE SUBUNIT), THROMBIN (SMALL SUBUNIT)
Authors:Vitali, J, Edwards, B.F.P.
Deposit date:1993-02-25
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution.
J.Biol.Chem., 267, 1992
1JZW
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BU of 1jzw by Molmil
Arsenate Reductase + Sodium Arsenate From E. coli
Descriptor: ARSENATE REDUCTASE, CESIUM ION, SULFATE ION, ...
Authors:Martin, P, DeMel, S, Shi, J, Gladysheva, T, Gatti, D.L, Rosen, B.P, Edwards, B.F.
Deposit date:2001-09-17
Release date:2001-11-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9, 2001
6N1O
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BU of 6n1o by Molmil
Oxidized rat cytochrome c mutant (S47E)
Descriptor: 1,2-ETHANEDIOL, Cytochrome c, somatic, ...
Authors:Huttemann, M, Edwards, B.F.P.
Deposit date:2018-11-09
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Serine-47 phosphorylation of cytochromecin the mammalian brain regulates cytochromecoxidase and caspase-3 activity.
Faseb J., 33, 2019
1YCP
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BU of 1ycp by Molmil
THE CRYSTAL STRUCTURE OF FIBRINOGEN-AA PEPTIDE 1-23 (F8Y) BOUND TO BOVINE THROMBIN EXPLAINS WHY THE MUTATION OF PHE-8 TO TYROSINE STRONGLY INHIBITS NORMAL CLEAVAGE AT ARGININE-16
Descriptor: ALPHA THROMBIN, EPSILON THROMBIN, FIBRINOPEPTIDE A-ALPHA
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-05-01
Release date:1998-05-06
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Biochem.J., 326, 1997

 

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