1HRT

THE STRUCTURE OF A COMPLEX OF BOVINE ALPHA-THROMBIN AND RECOMBINANT HIRUDIN AT 2.8 ANGSTROMS RESOLUTION

Summary for 1HRT

Entry DOI	10.2210/pdb1hrt/pdb
Descriptor	THROMBIN (SMALL SUBUNIT), THROMBIN (LARGE SUBUNIT), HIRUDIN, ... (4 entities in total)
Functional Keywords	serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00735 P00735 Secreted: P01050
Total number of polymer chains	3
Total formula weight	42481.17
Authors	Vitali, J.,Edwards, B.F.P. (deposition date: 1993-02-25, release date: 1994-01-31, Last modification date: 2011-07-13)
Primary citation	Vitali, J.,Martin, P.D.,Malkowski, M.G.,Robertson, W.D.,Lazar, J.B.,Winant, R.C.,Johnson, P.H.,Edwards, B.F. The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution. J.Biol.Chem., 267:17670-17678, 1992 Cited by PubMed: 1517214 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation