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6BWD
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BU of 6bwd by Molmil
3.7 angstrom cryoEM structure of truncated mouse TRPM7
Descriptor: CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, Transient receptor potential cation channel subfamily M member 7
Authors:Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E.
Deposit date:2017-12-14
Release date:2018-08-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BWI
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BU of 6bwi by Molmil
3.7 angstrom cryoEM structure of full length human TRPM4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
Authors:Zhang, J, Li, Z, Duan, J, Li, J, Clapham, D.E.
Deposit date:2017-12-15
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of full-length human TRPM4.
Proc.Natl.Acad.Sci.USA, 115, 2018
4GVA
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BU of 4gva by Molmil
ADP-bound form of the ERK2 kinase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitogen-activated protein kinase 1
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-30
Release date:2012-09-12
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:ADP-bound form of the ERK2 kinase
TO BE PUBLISHED
4GSB
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BU of 4gsb by Molmil
Monoclinic crystal form of the apo-ERK2
Descriptor: GLYCEROL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-27
Release date:2012-09-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Monoclinic crystal form of the apo-ERK2
TO BE PUBLISHED
6BWF
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BU of 6bwf by Molmil
4.1 angstrom Mg2+-unbound structure of mouse TRPM7
Descriptor: TRPM7
Authors:Zhang, J, Li, Z, Duan, J, Abiria, S.A, Clapham, D.E.
Deposit date:2017-12-14
Release date:2018-08-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8IW0
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BU of 8iw0 by Molmil
Crystal structure of the KANK1/liprin-beta1 complex
Descriptor: Liprin-beta-1,KN motif and ankyrin repeat domain-containing protein 1
Authors:Zhang, J, Chen, S, Wei, Z, Yu, C.
Deposit date:2023-03-29
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation.
Cell Rep, 42, 2023
8IW5
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BU of 8iw5 by Molmil
Crystal structure of liprin-beta H2H3 dimer
Descriptor: CALCIUM ION, Liprin-beta-1
Authors:Zhang, J, Chen, S, Wei, Z.
Deposit date:2023-03-29
Release date:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation.
Cell Rep, 42, 2023
7UR5
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BU of 7ur5 by Molmil
allo-tRNAUTu1 in the A, P, and E sites of the E. coli ribosome
Descriptor: allo-tRNAUTu1
Authors:Zhang, J, Krahn, N, Prabhakar, A, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-21
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7URI
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BU of 7uri by Molmil
allo-tRNAUTu1A in the A site of the E. coli ribosome
Descriptor: Allo-tRNAUTu1A
Authors:Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-22
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7URM
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BU of 7urm by Molmil
allo-tRNAUTu1A in the P site of the E. coli ribosome
Descriptor: allo-tRNAUTU1A
Authors:Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
Deposit date:2022-04-22
Release date:2022-08-10
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
3SM4
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BU of 3sm4 by Molmil
Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium
Descriptor: 5'-D(*TP*CP*GP*GP*TP*AP*CP*AP*GP*TP*AP*G)-3', 5'-D(P*AP*GP*CP*TP*AP*CP*TP*GP*TP*AP*CP*CP*GP*A)-3', CHLORIDE ION, ...
Authors:Bell, C.E, Zhang, J.
Deposit date:2011-06-27
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SLP
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BU of 3slp by Molmil
Crystal Structure of Lambda Exonuclease in Complex with a 12 BP Symmetric DNA Duplex
Descriptor: 5'-D(*GP*CP*GP*AP*CP*TP*AP*GP*TP*CP*GP*C)-3', CALCIUM ION, CHLORIDE ION, ...
Authors:Bell, C.E, Zhang, J.
Deposit date:2011-06-24
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA, 108, 2011
7X5V
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BU of 7x5v by Molmil
NaVEh Sodium channel, and NaVEh from the coccolithophore Emiliania huxleyi
Descriptor: ion channel, ion channel,GFP-TwinStrep
Authors:Jiang, D, Zhang, J.
Deposit date:2022-03-05
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:N-type fast inactivation of a eukaryotic voltage-gated sodium channel.
Nat Commun, 13, 2022
7YFH
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BU of 7yfh by Molmil
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
Deposit date:2022-07-08
Release date:2023-03-29
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFG
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BU of 7yfg by Molmil
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
Deposit date:2022-07-08
Release date:2023-03-29
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFI
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BU of 7yfi by Molmil
Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and glutamate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
Deposit date:2022-07-08
Release date:2023-03-29
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
5X5M
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BU of 5x5m by Molmil
Crystal structure of a hydrolase encoded by lin2189 from Listeria innocua
Descriptor: (+)-Yatakemycin, DIMETHYL SULFOXIDE, Lin2189 protein
Authors:Zhang, J.
Deposit date:2017-02-16
Release date:2017-12-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.211 Å)
Cite:GyrI-like proteins catalyze cyclopropanoid hydrolysis to confer cellular protection
Nat Commun, 8, 2017
7V3P
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BU of 7v3p by Molmil
Cryo-EM structure of the IGF1R/insulin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
Authors:Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C.
Deposit date:2021-08-11
Release date:2022-08-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the IGF1R/insulin complex
To Be Published
7DDE
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BU of 7dde by Molmil
Cryo-EM structure of the Ape4 and Nbr1 complex
Descriptor: Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
7DD9
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BU of 7dd9 by Molmil
Cryo-EM structure of the Ams1 and Nbr1 complex
Descriptor: Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
7UPY
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BU of 7upy by Molmil
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
Deposit date:2022-04-18
Release date:2022-08-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Sci Immunol, 7, 2022
7UPX
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BU of 7upx by Molmil
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SP1-77 Fab heavy chain, SP1-77 Fab light chain, ...
Authors:Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
Deposit date:2022-04-18
Release date:2022-08-10
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Sci Immunol, 7, 2022
7UPW
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BU of 7upw by Molmil
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
Deposit date:2022-04-18
Release date:2022-08-10
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Sci Immunol, 7, 2022
7CWE
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BU of 7cwe by Molmil
Human Fructose-1,6-bisphosphatase 1 in APO R-state
Descriptor: Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
Authors:Chen, Y, Zhang, J, Li, C, Cao, Y.
Deposit date:2020-08-28
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human Fructose-1,6-bisphosphatase 1 in APO R-state
To Be Published
4URT
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BU of 4urt by Molmil
The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R.
Deposit date:2014-07-02
Release date:2014-09-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue
Neuron, 83, 2014

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