4URT

The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC

Summary for 4URT

Entry DOI	10.2210/pdb4urt/pdb
Descriptor	NETRIN-1, NETRIN RECEPTOR DCC, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	protein binding, apoptosis, axon guidance, dependence receptor
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	73801.99
Authors	Finci, L.I.,Krueger, N.,Sun, X.,Zhang, J.,Chegkazi, M.,Wu, Y.,Schenk, G.,Mertens, H.D.T.,Svergun, D.I.,Zhang, Y.,Wang, J.-h.,Meijers, R. (deposition date: 2014-07-02, release date: 2014-09-10, Last modification date: 2024-01-10)
Primary citation	Finci, L.I.,Krueger, N.,Sun, X.,Zhang, J.,Chegkazi, M.,Wu, Y.,Schenk, G.,Mertens, H.D.T.,Svergun, D.I.,Zhang, Y.,Wang, J.-H.,Meijers, R. The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue Neuron, 83:839-, 2014 Cited by PubMed: 25123307 DOI: 10.1016/J.NEURON.2014.07.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation