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7PQG
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BU of 7pqg by Molmil
Structure of thermostabilised human NTCP in complex with nanobody 87
Descriptor: Nanobody 87, Sodium/bile acid cotransporter
Authors:Goutam, K, Reyes, N.
Deposit date:2021-09-21
Release date:2022-05-18
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of sodium-dependent bile salt uptake into the liver.
Nature, 606, 2022
7Q1U
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BU of 7q1u by Molmil
Structure of Hedgehog acyltransferase (HHAT) in complex with megabody 177 bound to non-hydrolysable palmitoyl-CoA (Composite Map)
Descriptor: CHOLESTEROL, MAGNESIUM ION, Megabody 177, ...
Authors:Coupland, C, Carrique, L, Siebold, C.
Deposit date:2021-10-21
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Mol.Cell, 81, 2021
6GS7
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BU of 6gs7 by Molmil
Crystal structure of peptide transporter DtpA-nanobody in glycine buffer
Descriptor: Dipeptide and tripeptide permease A, nanobody
Authors:Ural-Blimke, Y, Flayhan, A, Quistgaard, E.M, Loew, C.
Deposit date:2018-06-13
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
J. Am. Chem. Soc., 141, 2019
5N7O
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BU of 5n7o by Molmil
EthR2 in complex with SMARt-420 compound
Descriptor: 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)butan-1-one, Probable transcriptional regulatory protein
Authors:Wohlkonig, A, Wintjens, R.
Deposit date:2017-02-21
Release date:2017-04-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.
Biochem. Biophys. Res. Commun., 487, 2017
6QPG
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BU of 6qpg by Molmil
Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205
Descriptor: Nanobody NB8205, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M.
Deposit date:2019-02-13
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6QXE
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BU of 6qxe by Molmil
Influenza A virus (A/NT/60/1968) polymerase dimer of hetermotrimer in complex with 3'5' cRNA promoter and Nb8205
Descriptor: Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
Deposit date:2019-03-07
Release date:2019-09-04
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6QX8
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BU of 6qx8 by Molmil
Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*CP*AP*AP*AP*AP*GP*CP*AP*GP*A)-3'), ...
Authors:Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
Deposit date:2019-03-07
Release date:2019-09-04
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6HLU
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BU of 6hlu by Molmil
Crystal structure of the LRR-Roc-COR domain of the Chlorobium tepidum Roco protein
Descriptor: Rab family protein
Authors:Deyaert, E, Versees, W, Singh, R.
Deposit date:2018-09-11
Release date:2018-12-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structure and nucleotide-induced conformational dynamics of theChlorobium tepidumRoco protein.
Biochem. J., 476, 2019
6HER
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BU of 6her by Molmil
Mouse prion protein in complex with Nanobody 484
Descriptor: GLYCEROL, Major prion protein, Nanobody 484, ...
Authors:Soror, S.H, Abskharon, R, Wohlkonig, A.
Deposit date:2018-08-20
Release date:2019-12-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
6HHD
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BU of 6hhd by Molmil
Mouse Prion Protein in complex with Nanobody 484
Descriptor: CHLORIDE ION, GLYCEROL, Major prion protein, ...
Authors:Soror, S, Abskharon, R, Wohlkonig, A.
Deposit date:2018-08-28
Release date:2019-12-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
5IOF
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BU of 5iof by Molmil
Structure of the transmembrane domain of the transporter SLC26Dg
Descriptor: Sulphate transporter
Authors:Dutzler, R, Geertsma, E.R.G, Shaik, F.R.
Deposit date:2016-03-08
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.
Nat. Struct. Mol. Biol., 22, 2015
2LAL
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BU of 2lal by Molmil
CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT AT 2.3 ANGSTROMS RESOLUTION OF THE LENTIL LECTIN
Descriptor: CALCIUM ION, LENTIL LECTIN (ALPHA CHAIN), LENTIL LECTIN (BETA CHAIN), ...
Authors:Loris, R, Steyaert, J, Maes, D, Lisgarten, J, Pickersgill, R, Wyns, L.
Deposit date:1993-06-10
Release date:1993-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of two crystal forms of lentil lectin at 1.8 A resolution.
Proteins, 20, 1994
3MKM
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BU of 3mkm by Molmil
Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)
Descriptor: CALCIUM ION, Putative uncharacterized protein YeiK
Authors:Garau, G, Fornili, A, Giabbai, B, Degano, M.
Deposit date:2010-04-15
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures
J.Am.Chem.Soc., 132, 2010
5N1I
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BU of 5n1i by Molmil
unliganded form of the Mycobacterium tuberculosis repressor EthR2
Descriptor: Probable transcriptional regulatory protein
Authors:Wintjens, R, Wohlkonig, A.
Deposit date:2017-02-06
Release date:2017-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Science, 355, 2017
4DK3
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BU of 4dk3 by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DKA
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BU of 4dka by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, SODIUM ION, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
5N1C
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BU of 5n1c by Molmil
Iodinated form of the Mycobacterium tuberculosis repressor EthR2
Descriptor: IODIDE ION, Probable transcriptional regulatory protein
Authors:Wintjens, R, Wohlkonig, A.
Deposit date:2017-02-06
Release date:2017-04-26
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Science, 355, 2017
4DK6
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BU of 4dk6 by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
5OCL
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BU of 5ocl by Molmil
Nanobody-anti-VGLUT nanobody complex
Descriptor: anti-llama nanobody, anti-vglut nanobody
Authors:Dutzler, R, Schenck, S, Kunz, L.
Deposit date:2017-07-03
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.
Biochemistry, 56, 2017
1Q8F
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BU of 1q8f by Molmil
Crystal Structure of the E.coli pyrimidine nucleoside hydrolase yeiK
Descriptor: CALCIUM ION, GLYCEROL, Pyrimidine nucleoside hydrolase
Authors:Giabbai, B, Degano, M.
Deposit date:2003-08-21
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy.
STRUCTURE, 12, 2004
6H02
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BU of 6h02 by Molmil
Crystal structure of human Mediator subunit MED23
Descriptor: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23
Authors:Clantin, B, Monte, D, Villeret, V.
Deposit date:2018-07-06
Release date:2018-08-29
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human Mediator subunit MED23.
Nat Commun, 9, 2018
4M3K
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BU of 4m3k by Molmil
Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4M3J
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BU of 4m3j by Molmil
Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4N1H
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BU of 4n1h by Molmil
Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-10-04
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4GGN
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BU of 4ggn by Molmil
Malaria invasion machinery protein complex
Descriptor: Myosin A tail domain interacting protein MTIP, Myosin-A
Authors:Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J.
Deposit date:2012-08-06
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013

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