7PQG

Structure of thermostabilised human NTCP in complex with nanobody 87

Summary for 7PQG

Entry DOI	10.2210/pdb7pqg/pdb
EMDB information	13593
Descriptor	Nanobody 87, Sodium/bile acid cotransporter (2 entities in total)
Functional Keywords	slc10a1, sodium bile acid symporter, membrane protein
Biological source	Lama glama More
Total number of polymer chains	2
Total formula weight	51640.87
Authors	Goutam, K.,Reyes, N. (deposition date: 2021-09-21, release date: 2022-05-18, Last modification date: 2022-07-06)
Primary citation	Goutam, K.,Ielasi, F.S.,Pardon, E.,Steyaert, J.,Reyes, N. Structural basis of sodium-dependent bile salt uptake into the liver. Nature, 606:1015-1020, 2022 Cited by PubMed: 35545671 DOI: 10.1038/s41586-022-04723-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation