6QPG

Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205

Summary for 6QPG

• Entry DOI: 10.2210/pdb6qpg/pdb
• Descriptor: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (4 entities in total)
• Functional Keywords: influenza a, rna polymerase, influenza polymerase, influenza dimer, rdrp, nanobody, antiviral inhibitor, rna binding protein
• Biological source: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60)); More
• Total number of polymer chains: 16
• Total formula weight: 1085674.00

Authors

Fan, H.T.,Keown, J.R.,Fodor, E.,Grimes, J.M. (deposition date: 2019-02-13, release date: 2019-09-04, Last modification date: 2024-01-24)

• Primary citation: Fan, H.,Walker, A.P.,Carrique, L.,Keown, J.R.,Serna Martin, I.,Karia, D.,Sharps, J.,Hengrung, N.,Pardon, E.,Steyaert, J.,Grimes, J.M.,Fodor, E.; Structures of influenza A virus RNA polymerase offer insight into viral genome replication.; Nature, 573:287-290, 2019; PubMed: 31485076; DOI: 10.1038/s41586-019-1530-7

Experimental method

X-RAY DIFFRACTION (3.34 Å)