5N1I

unliganded form of the Mycobacterium tuberculosis repressor EthR2

Replaces:  5N1C

Summary for 5N1I

• Entry DOI: 10.2210/pdb5n1i/pdb
• Related: 5ICJ 5N1C
• Descriptor: Probable transcriptional regulatory protein (2 entities in total)
• Functional Keywords: repressor, ethr, dna binding protein, tetr protein family.
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 2
• Total formula weight: 48245.14

Authors

Wintjens, R.,Wohlkonig, A. (deposition date: 2017-02-06, release date: 2017-04-26, Last modification date: 2024-02-07)

• Primary citation: Blondiaux, N.,Moune, M.,Desroses, M.,Frita, R.,Flipo, M.,Mathys, V.,Soetaert, K.,Kiass, M.,Delorme, V.,Djaout, K.,Trebosc, V.,Kemmer, C.,Wintjens, R.,Wohlkonig, A.,Antoine, R.,Huot, L.,Hot, D.,Coscolla, M.,Feldmann, J.,Gagneux, S.,Locht, C.,Brodin, P.,Gitzinger, M.,Deprez, B.,Willand, N.,Baulard, A.R.; Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.; Science, 355:1206-1211, 2017; PubMed: 28302858; DOI: 10.1126/science.aag1006

Experimental method

X-RAY DIFFRACTION (2.4 Å)