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6GFJ
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BU of 6gfj by Molmil
Structure of RIP2 CARD domain fused to crystallisable MBP tag
Descriptor: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pellegrini, E, Cusack, S.
Deposit date:2018-04-30
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
4WSB
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BU of 4wsb by Molmil
Bat Influenza A polymerase with bound vRNA promoter
Descriptor: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ...
Authors:Cusack, S, Pflug, A, Guilligay, D, Reich, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4WRT
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BU of 4wrt by Molmil
Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2)
Descriptor: Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ...
Authors:Reich, S, Guilligay, D, Pflug, A, Cusack, S.
Deposit date:2014-10-25
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4WSA
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BU of 4wsa by Molmil
Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form)
Descriptor: Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ...
Authors:Reich, S, Guilligay, D, Pflug, A, Cusack, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
6Z6B
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BU of 6z6b by Molmil
Structure of full-length La Crosse virus L protein (polymerase)
Descriptor: RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ...
Authors:Cusack, S, Gerlach, P, Reguera, J.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
5AMR
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BU of 5amr by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' viral RNA
Descriptor: RNA, RNA POLYMERASE L
Authors:Reguera, J, Gerlach, P, Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell(Cambridge,Mass.), 161, 2015
5AMQ
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BU of 5amq by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' and 5' viral RNA
Descriptor: RNA, RNA POLYMERASE L
Authors:Reguera, J, Gerlach, P, Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell, 161, 2015
6SZA
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BU of 6sza by Molmil
MoxR AAA-ATPase RavA, C2-symmetric closed ring conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RavA
Authors:Jessop, M, Felix, J, Gutsche, I.
Deposit date:2019-10-02
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6SZB
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BU of 6szb by Molmil
MoxR AAA-ATPase RavA, spiral open ring conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RavA + Mg-ADP
Authors:Jessop, M, Felix, J, Gutsche, I.
Deposit date:2019-10-02
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
2P3L
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BU of 2p3l by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with GpppA and S-Adenosyl-L-Homocysteine
Descriptor: CITRIC ACID, GLYCEROL, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ...
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3O
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BU of 2p3o by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppA and S-Adenosyl-L-homocysteine
Descriptor: CITRIC ACID, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P40
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BU of 2p40 by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, SULFATE ION, type II methyltransferase
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P41
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BU of 2p41 by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG2'OMe and S-Adenosyl-L-homocysteine
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-GUANOSINE, CITRIC ACID, GLYCEROL, ...
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3Q
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BU of 2p3q by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with GpppG and S-Adenosyl-L-homocysteine
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
5JCH
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BU of 5jch by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.95 A resolution (untwinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBG
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BU of 5jbg by Molmil
Crystal structure of chicken LGP2 with 5'ppp 26-mer hairpin RNA with 3' GG overhang and ADP-AlF4-Mg2+ at 2.0 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBJ
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BU of 5jbj by Molmil
Crystal structure of chicken LGP2 with 5'p 12-mer dsRNA at 3.6 A resolution
Descriptor: LGP2, RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3'), ZINC ION
Authors:Cusack, S, Uchikawa, E, Lethier, M.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC3
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BU of 5jc3 by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JCF
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BU of 5jcf by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (orthorhombic form).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC7
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BU of 5jc7 by Molmil
Crystal structure of chicken MDA5 with 5'p 24-mer dsRNA and ADP-Mg2+ at 2.75 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JAJ
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BU of 5jaj by Molmil
Structure of chicken LGP2 witha 5'p 10-mer dsRNA and ADP-AlF4-Mg.
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, LGP2, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-12
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JB2
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BU of 5jb2 by Molmil
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5ISN
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BU of 5isn by Molmil
NMR solution structure of macro domain from Venezuelan equine encephalitis virus
Descriptor: Non-structural polyprotein
Authors:Makrynitsa, G.I, Ntonti, D, Marousis, K.D, Tsika, A.C, Papageorgiou, N, Coutard, B, Bentrop, D, Spyroulias, G.A.
Deposit date:2016-03-15
Release date:2017-11-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
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