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2P40

Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG

Summary for 2P40
Entry DOI10.2210/pdb2p40/pdb
Related1L9K 2P1D 2P3L 2P3O 2P3Q 2P41
Descriptortype II methyltransferase, SULFATE ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ... (4 entities in total)
Functional Keywordsvizier; viral enzymes involved in replication; dengue virus methyltransferase; structural genomics; marseilles structural genomics program @ afmb; msgp, viral protein, transferase
Biological sourceDengue virus 2
Cellular locationEnvelope protein E: Virion membrane; Multi- pass membrane protein: Q9WLZ8
Total number of polymer chains1
Total formula weight36257.16
Authors
Egloff, M.P.,Marseilles Structural Genomics Program @ AFMB (MSGP) (deposition date: 2007-03-11, release date: 2007-08-28, Last modification date: 2023-08-30)
Primary citationEgloff, M.P.,Decroly, E.,Malet, H.,Selisko, B.,Benarroch, D.,Ferron, F.,Canard, B.
Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372:723-736, 2007
Cited by
PubMed: 17686489
DOI: 10.1016/j.jmb.2007.07.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.701 Å)
Structure validation

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