5JB2
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Summary for 5JB2
Entry DOI | 10.2210/pdb5jb2/pdb |
Descriptor | LGP2, RNA (5'-R(*GPPP*GP*UP*AP*CP*GP*UP*AP*CP*CP*C)-3'), RNA (5'-R(*GPPP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ... (8 entities in total) |
Functional Keywords | innate immune pattern recognition receptor, rig-i like helicase, dsrna dependent atpase, zinc-containing ctd domain, immune system |
Biological source | Gallus gallus (Chicken) More |
Total number of polymer chains | 3 |
Total formula weight | 85082.19 |
Authors | Cusack, S.,Uchikawa, E. (deposition date: 2016-04-13, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Uchikawa, E.,Lethier, M.,Malet, H.,Brunel, J.,Gerlier, D.,Cusack, S. Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5. Mol.Cell, 62:586-602, 2016 Cited by PubMed: 27203181DOI: 10.1016/j.molcel.2016.04.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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